Insertions and deletions mold #coenzyme specificity in #Rossmann #enzymes.
#RNAworld #evolution #proteins
https://phys.org/news/2022-11-insertions-deletions-mold-coenzyme-specificity.html
#coenzyme #rossmann #enzymes #RNAworld #evolution #proteins
#InDels reshape #coenzyme specificity in #Rossmann #fold #enzymes from NAD-binding to SAM-binding
https://www.pnas.org/doi/10.1073/pnas.2207965119
#proteinengineering #proteinevolution #catalysis #moleculardynamics #xraycrystallography #PNAS
#indels #coenzyme #rossmann #fold #Enzymes #proteinengineering #proteinevolution #catalysis #moleculardynamics #Xraycrystallography #pnas