Last talk of the #CSSingleCells23 conference:
Karin Pelka, Gladstone/UCSF
https://gladstone.org/people/karin-pelka

Spatially organized #immune hubs in #colon #cancer
#ColonCancer
#scRNAseq

https://pubmed.ncbi.nlm.nih.gov/34450029/

Then: predict cellular interaction networks via correlations of gene program activities across #tumors

anti-tumor hubs in tumors, ISGs including CXCR3 ligands, differs between tumor types (MMR+ or -)

have data from clinical trial (biopsies before and after treatment)
https://pubmed.ncbi.nlm.nih.gov/36702949/

1/2

Really saddened to hear about #JamesCasey dying. As some of you know, my brother also died of #ColonCancer at a too-young age. Please take the time to learn about your family history and do some screening if there is the slightest cause for concern. I've been getting colonoscopies since my mid 20s and they really aren't that bad. #CancerSucks #Cancer #CancerAwareness

Conclusion: Efforts to reduce the number of patients who need to undergo a diverting ostomy could result in meaningful cost savings.

#ostomy #stoma #coloncancer

Link to paper: https://pubmed.ncbi.nlm.nih.gov/37580581/

https://herbalremedies.one/how-to-cleanse-your-colon-naturally/ What is a Colon Cleanse? Naturally Cleansing your colon helps you not only prevent colorectal cancer, the 3rd most lethal type of cancer but it can also help you prevent appendicitis, reverse chronic fatigue, bloating, gas, sour stomach and IBS. You can lose weight naturally by flushing the toxic sludge stuck in your body as impacted material and intestinal plaque. Your skin tone will also improve and you'll look and feel more vibrant that you have in a long time. #cleanse #coloncleanse #coloncancer #detox #health

At fifty, start testing
Screening for colon cancer
Need of prevention

#coloncancer #screening #healthcare #prevention #haiku #poetry

http://www.medicalnewstoday.com/articles/colorectal-cancer-screening-can-start-at-age-50-acp-guidelines

RT: Excellent review on the current management of patients with metastatic #coloncancer and future combined strategies.
https://mdpi.com/1718-7729/30/7/480

https://twitter.com/Dr_Ivanoncologo/status/1677337248835018757?s=20

"There was some sort of exposure we think in the 1970s or 1980s — maybe everybody started taking antibiotics for ear infections or they stopped breastfeeding — something happened where this cohort is seeing this rise and we don't know why."

https://www.axios.com/2023/05/26/new-bacterial-clues-young-people-colorectal-cancer?utm_campaign=KHN%3A%20First%20Edition&utm_medium=email&_hsmi=259981925&_hsenc=p2ANqtz-8seC5wC7uSnsF51faEB5iVg288eaaW2NPT6KmMgjYrTrTsXsZAnUsEYLjDuRtg3cNK469ekQfI8ONFacFzf8r2ARhmgw&utm_content=259981925&utm_source=hs_email

#primarycare #prevention #coloncancer

New research identifies earliest signs of colon cancer

#health #ColonCancer

https://www.youtube.com/watch?v=EtSH5_Y3Fws

Our Alternative Cancer Treatment clinic offers highly customized care for patients with #breastcancer #coloncancer #pancreaticcancer #lungcancer #melanoma, and more. We don't treat #cancer. We treat the cause!

This means we do a lot of testing and labs to determine which therapies and supplements will be right for you.

You can learn more about our clinic at ConnersClinic.com

There is hope. Request a case review today!

My husband has stage 4 cancer. We're fundraising to support him through surgery that could save his life. Please share if you have a moment - it would really help us out.

https://www.gofundme.com/f/support-mathew-through-his-bowel-cancer-surgery

#bowelcancer #coloncancer #fundraiser #coloncancerawarenessmonth

RT @RischZack
@TumorBoardTues @MPishvaian @JohnEbbenMDPhD @CCAlliance @shafiarahman_ @ASCO @NatureMedicine @YoshinoriKagawa 6/22 #TumorBoardTuesday
#ColonCancer
Back to case🔎
👨🏼‍Pmab added to FOLFOX after 1 cycle

📌Data for 1L Anti-EGFR inhibitor
👍🏽Several prior trials signal OS benefit of anti-EGFR tx in L side KRAS WT
❓Is frontline anti-EGFR essential in fit unresectable👨🏾‍ given clinical➕💰tox

Global News BC: B.C. colon cancer survivor speaks out about life-altering diagnosis https://globalnews.ca/news/9571443/colon-cancer-awareness-story/ #globalnews #britishcolumbia #news #ColorectalCancerAwarenessMonth #ColonCancerAwarenessMonth #ColorectalCancer #CancerScreening #cancersuvival #coloncancer #Screening #Health #Cancer #News

#ColonCancer has always been more of a risk for older persons. But as #obesity rises in young persons, colon cancer is on its way to becoming the deadliest cancer for people under 50. The good news: we have effective options for dealing with this.
https://conscienhealth.org/2023/03/colon-cancer-and-obesity-in-young-persons/

RT @TumorBoardTues
#PreTest Q 1️⃣ #TumorBoardTuesday
Free #CME 🔗 http://integrityce.com/tbt

We’re back to GI oncology this week with @shafiarahman_ @RischZack to discuss EGFR!

Test your 🧠 with these❓

🤔What 1L tx would you pick for 62yo👨🏾‍🦳
ASx, L-side met #ColonCancer - unresectable liver mets?

RT @TumorBoardTues
#PreTest Q2️⃣ #TumorBoardTuesday @MPishvaian @JohnEbbenMDPhD @CCAlliance #ColonCancer #CRCAwarenessMonth
#CME 🔗 http://integrityce.com/tbt

🔬Path results for above 👨🏾‍🦳 who has undergone 1 cycle of FOLFOX
Disease KRAS wild type.

🤔What agent would you add to his treatment regimen?

RT @RischZack
@TumorBoardTues @MPishvaian @JohnEbbenMDPhD @CCAlliance @shafiarahman_ @ASCO @NatureMedicine @YoshinoriKagawa 6/22 #TumorBoardTuesday
#ColonCancer
Back to case🔎
👨🏼‍Pmab added to FOLFOX after 1 cycle

📌Data for 1L Anti-EGFR inhibitor
👍🏽Several prior trials signal OS benefit of anti-EGFR tx in L side KRAS WT
❓Is frontline anti-EGFR essential in fit unresectable👨🏾‍ given clinical➕💰tox

RT @RischZack
@TumorBoardTues @MPishvaian @JohnEbbenMDPhD @CCAlliance @shafiarahman_ @ASCO @NatureMedicine @YoshinoriKagawa 6/22 #TumorBoardTuesday
#ColonCancer
Back to case🔎
👨🏼‍Pmab added to FOLFOX after 1 cycle

📌Data for 1L Anti-EGFR inhibitor
👍🏽Several prior trials signal OS benefit of anti-EGFR tx in L side KRAS WT
❓Is frontline anti-EGFR essential in fit unresectable👨🏾‍ given clinical➕💰tox

📢GI returns!!
This week’s #TumorBoardTuesday is here in time for #CRCAwarenessMonth!!

🥼@shafiarahman_ @RischZack teach us EGFR in #ColonCancer
👇🏽👇🏽

📱Weigh in your answers
🧾Bring receipts
🙋Ask Q’s
📊check polls
🔁RT
👩🏻‍⚕️tag peers👨🏻‍⚕️
@MPishvaian @JohnEbbenMDPhD
#MedTwitter
---
RT @RischZack
@TumorBoardTues @MPishvaian @JohnEbbenMDPhD @CCAlliance 1/22 #TumorBoardTuesday #ColonCancerAwarenessMonth #OncTwitter @shafiarahman_

62 yo 👨🏼‍🦳 a…
https://twitter.com/RischZack/status/1638330517530574851

#PreTest Q2️⃣ #TumorBoardTuesday @MPishvaian @JohnEbbenMDPhD @CCAlliance #ColonCancer #CRCAwarenessMonth
#CME 🔗 http://integrityce.com/tbt

🔬Path results for above 👨🏾‍🦳 who has undergone 1 cycle of FOLFOX
Disease KRAS wild type.

🤔What agent would you add to his treatment regimen?

#PreTest Q 1️⃣ #TumorBoardTuesday
Free #CME 🔗 http://integrityce.com/tbt

We’re back to GI oncology this week with @shafiarahman_ @RischZack to discuss EGFR!

Test your 🧠 with these❓

🤔What 1L tx would you pick for 62yo👨🏾‍🦳
ASx, L-side met #ColonCancer - unresectable liver mets?