The EMBO Journal · @embojournal
460 followers · 218 posts · Server sciencemastodon.com
#Cohesin can resolve sister #chromatids already in G2 phase independent of #condensin - suggesting DNA #loopextrusion as generic mechanism for segregating #replicated genomes shared across different Structural Maintenance of #Chromosomes (SMC) protein complexes
Paul Batty, Daniel Gerlich et al #viennabiocenter
https://www.embopress.org/doi/10.15252/embj.2023113475
#cohesin #chromatids #condensin #loopextrusion #replicated #Chromosomes #viennabiocenter
The EMBO Journal · @embojournal
321 followers · 44 posts · Server sciencemastodon.com
How does #condensin #SMC complex extrude #DNA loops?
Joaquim Roca and coworkers show that it generates DNA #translocation steps by pinching a short negatively #supercoiled DNA loop during each round of #ATP #hydrolysis
https://www.embopress.org/doi/10.15252/embj.2022111913
#condensin #smc #dna #Translocation #supercoiled #atp #hydrolysis
Atreya Dey · @at_ray_o
13 followers · 1 posts · Server sciencemastodon.comHello everyone! I am Atreya, a PhD candidate in UT Austin. I had been lurking here for some time, and finally decided to write about myself. My research is on #3dgenome and #condensin. I am also dabbling in #deeplearning for some time. Apart from research, I like talking about #darkskies #photography and #scicomm.
#3dgenome #condensin #deeplearning #darkskies #photography #scicomm