The first monomeric structure of CRM197, a genetically detoxified mutant of diphtheria toxin that is widely used as a carrier protein in conjugate vaccines, is reported and compared with its dimeric counterparts. #Carriers #ConjugateVaccines #CRM197 https://doi.org/10.1107/S2053230X23002364

D​. Travis Gallagher et al.: Monomeric crystal structure of the vaccine carrier protein CRM197 and implications for vaccine development #Carriers #ConjugateVaccines #CRM197 ... #IUCr http://scripts.iucr.org/cgi-bin/paper?S2053230X23002364