A link between #Smoothened #cholesterylation and #endoplasmic #reticulum exit in #Hedgehog signaling: #GRAMD1-mediated #cholesterol transfer and Smoothened modification accelerates it #COPII-dependent ER exit and promotes signaling
https://www.embopress.org/doi/10.15252/embj.2022111513
#smoothened #cholesterylation #endoplasmic #reticulum #hedgehog #gramd1 #cholesterol #copii