@medrxivpreprint
The commonly used #antibiotics #amoxicillin, #metronidazole, #piperacillin-tazobactam & #Clindamycin reached levels equivalent to blood within infected pleural fluid.Low penetration of trimethoprim into the pleural space raised concerns about the use of #cotrimoxazole for patients with #Pleuralinfection or parapneumonic effusions.
#Antibiotic #pharmacokinetics in infected #pleuraleffusions
https://www.medrxiv.org/content/10.1101/2023.09.08.23295282v1.full.pdf
#antibiotics #Amoxicillin #metronidazole #piperacillin #clindamycin #cotrimoxazole #pleuralinfection #antibiotic #pharmacokinetics #pleuraleffusions
More cotrimoxazole use as prophylaxis in people living with HIV (PLWHIV) 👉 more cotrimoxazole resistance.
Predictable but important reminder that even justified antibiotic consumption has consequences. 🎯
🌟 Use antibiotics wisely! 🌟
#IDMastodon #AMR #MedMastodon #antimicrobialstewardship #septrin #bactrim #cotrimoxazole #HIV
https://academic.oup.com/cid/advance-article-abstract/doi/10.1093/cid/ciac978/6968505
#IDMastodon #AMR #MedMastodon #antimicrobialstewardship #septrin #bactrim #cotrimoxazole #hiv