Procalcitonin & C-reactive protein in critically ill patients with pneumonia associated to #COVID19?
🇪🇸 55 Spanish ICUs
🏥 > 4K patients included
🧫 3% presented bacterial coinfection
🧪 a single measurement of either PCT & CRP alone is not enough to rule out bacterial coinfection. Considering combined values of these biomarkers + symptoms timing & broader clinical context, appears to be relevant in their interpretation.
Open access #FOAMcc #COVIDFOAM on @ICM
🖇️ https://rdcu.be/dh9ex

🦠 3 years after the onset of #pandemic, here an expert consensus on evolving role of VV #ECMO for #COVID19 related severe #ARDS:
📃 14 statements on patient selection, #ethics, and clinical, logistic & operational #ECLS management, to be used to guide providers during future pandemics.
Open access #FOAMcc #FOAMecmo #COVIDFOAM
🖇️ https://bit.ly/42eMxYz

Intracannula thrombosis in patients with #COVID19 associated respiratory failure on oxy-RVAD. A case series detailing thrombus formation within dual lumen RA to PA #ECMO cannula. In all patients thrombus developed in the setting of an additional venous cannula.
Open access on ASAIO Journal #FOAMcc #FOAMecmo #COVIDFOAM
🖇️ http://bit.ly/3IVGIr2

Long-term outcomes of patients with acute hypoxemic respiratory failure due to #COVID19 pneumonia, follow-up study of the Helmet-COVID RCT. Helmet noninvasive ventilation compared to usual respiratory support:
↔️ did not decrease 180-day mortality
↔️ did not improve health-related quality of life
➡️ invasive mechanical ventilation independent predictor of lower HRQoL
Free to read #FOAMcc #COVIDFOAM on @ICM
🖇️ https://rdcu.be/c6ioV

🦠 Outcomes of #ECMO for COVID19 vs non-COVID related viral #ARDS? Substantially different prognosis! According to this ELSO Registry analysis, longer run, more complications, higher rate of death on #ECLS and statistically higher overall in-hospital mortality for patients with #SARSCoV2 compared with patients with other viral pathogens. Open access #FOAMcc #FOAMecmo #COVIDFOAM
📖 http://bit.ly/3RMbhna

#ECMO for #COVID19 related #ARDS, narrative review:
➡️ #ECLS
➡️ evidence for extracorporeal support in ARDS management
➡️ VV & VA
➡️ special populations: pregnant patients, children #PedsICU
➡️ prolonged ECMO & lung #transplantation
Open access #FOAMcc #FOAMecmo #COVIDFOAM
🖇️ http://bit.ly/3IalmqB

#SARSCoV2 infection? Vaccination effective to reduce risk of death in #ICU patients with severe respiratory failure associated to #COVID19 requiring ventilatory support: results from multicenter study enrolling patients from 27 🇮🇹 ICUs.
Free to read #FOAMcc #COVIDFOAM on
🖇️ https://rdcu.be/c4cb3

Evaluating accuracy of ROX & PROX ( = pressure respiratory rate oxygenation index = ratio between oxygenation parameter, assessed by SpO2/FiO2, & product of respiratory rate x PEEP) in predicting negative outcome in #COVID19 relate hypoxemic respiratory failure.
🖇️ https://rdcu.be/c3afK

PS on ROX also read
🖇️ https://rdcu.be/cYtuF

All free to read #FOAMcc #COVIDFOAM on @ICM

#ECLS provision in #COVID19, international @EuroELSO 2022 update survey:
📈 majority of pts received #ECMO for respiratory support
📈 adults dominated
📊 indications/contraindications aligned with available guidelines
📉 most of centers considered age > 65 or biological age as contraindication for ECLS
📉 withdrawal criteria difficult to define as long-term outcomes, impact of critical illness & of long-COVID still not known
Open #FOAMcc #FOAMecmo #COVIDFOAM #EuroELSO2023
📎 https://bit.ly/3ZqOror

🏥 Acute disease severity in #COVID19: patients who needed mechanical ventilation during hospital stay had significantly lower health‐related quality of life & worse results for mortality, major cardiovascular events, re‐hospitalisation, new disabilities in instrumental activities of daily living, anxiety and post‐traumatic stress symptoms, and return to work or study vs pts who did not need MV. Full results of coalition VII 🇨🇬 prospective cohort study #FOAMcc #COVIDFOAM
🗞️ https://rdcu.be/c2WsP

#ECMO during #COVID19, The Society of Thoracic Surgeons STS & @ELSO Extracorporeal Life Support Organization collaborative survey comparing practices related to ECMO initiation, cannulation, management, anticoagulation,
triage/protocols, credentialing before/during #pandemic in North American ELSO centers.
Pandemic affected #ECLS practice! Full results open access #FOAMcc #FOAMecmo #COVIDFOAM at
📎 https://bit.ly/3GgwHo4

Early reversal of RV dysfunction after VV #ECMO in patients with #COVID19 related refractory #ARDS?? #Extracorporeal support initiation associated with rapid decrease in pulmonary artery pressure, improvement of right ventricular function & resolution of ACP-induced circulatory failure.
Open access #FOAMcc #COVIDFOAM
📎 https://bit.ly/3XXbQ04

Mental health symptom in survivors of severe #COVID19 related #ARDS? Occurrence of symptoms of anxiety, depression or PTSD poorly correlated with peripheral inflammatory biomarkers concentrations. Until #PTSD-specific biomarkers can be identified & validated in this setting, early screening of mental health symptoms should be offered regardless concentrations of initial inflammatory biomarkers.
Free to read #FOAMcc #COVIDFOAM on @ICM
📎 https://rdcu.be/c0VFk