Researchers Discover Quantum Switch For Regulating Photosynthesis https://thequantuminsider.com/?p=2358217 #Research #bioengineering #cryoEM #LHCII #lightharvesting #photosynthesis #plants #quantum_channel #quantumdaily Insider Brief Researchers identify the photosynthetic pigment quantum switch for intermolecular energy transfer. They studied light-harvesting complex II (LHCII) is a complex of pigment molecules bound to proteins. A rapid response to changes in light intensity causes both high

Mapping of a gut #virus by #cryoEM:

https://phys-org.cdn.ampproject.org/c/s/phys.org/news/2023-05-first-ever-human-gut-virus.amp

RT @RubinsteinJohn
Mycobacteria possess a branched and flexible electron transport chain
In her review in #BiochemSocTrans, @think_zesty shows how #cryoEM is helping to reveal the sophistication of mycobacterial respiration, and how it can be targeted to treat #tuberculosis
https://portlandpress.com/biochemsoctrans/article-abstract/doi/10.1042/BST20220611/232478/Structural-analysis-of-mycobacterial-electron?redirectedFrom=fulltext

New paper about #NMR assignment of a tau fibrils similar to those found in #Alzheimer'sdisease. Also includes ideas how to compare #NMR data with known #cryoEM structures. https://doi.org/10.3389/fnins.2022.988074

RT @SjorsScheres
#CryoEM structure of the complete inner kinetochore of the budding yeast point centromere. An amazing set of structures from the Barford lab @MRC_LMB, including results from our newest tool by Johannes Schwab to handle structural flexibility. 🥳

https://www.biorxiv.org/content/10.1101/2022.12.12.520091v1

RT @a_punjani
Super excited to release 3D Flexible Refinement in beta in #CryoSPARC! Looking forward to seeing hopefully lots of interesting #CryoEM results that users are able to get! https://twitter.com/structurabio/status/1602352738100445184

RT @Jayquerido
Excited to share our new preprint (Brito Querido et al).
The structure of a human translation initiation complex reveals a second molecule of the helicase eIF4A at the mRNA entry site, on the opposite side of the 43S from eIF4F. https://www.biorxiv.org/content/10.1101/2022.12.07.519490v1
#CryoEM #science #mRNA

RT @MPIbp
New insights into mitochondrial complex I by #CryoEM published by our Structural Biology Department in cooperation with our Langer Lab in @ScienceAdvances: The giant enzyme undergoes a transition between two states characterised by a twisting motion and substantial restructuring.

For the #cryoem, #cryoet, and #structuralbiology folks out there, #SBGrid just posted a video on the #opensource #software tool TomoTwin-cryoet. Thanks to Thorsten Wagner from Max-Planck-Institute of Molecular Physiology for joining us to introduce this new tool.

Watch here: https://www.youtube.com/watch?v=7pZyRpoUEaA

For SBGrid members, you can now find TomoTwin-cryoet in your software installations

RT @PiperProteins
#Render of the week is presenting a short molecular dynamics animation on #GPCR peptide binding process, prepared in @Blender using @bradyajohnston MolecularNodes, showing the ligand peptide (in blue) and receptor in black! #MD and #CryoEM data based on our recent paper 👇 (1/2)

RT @GatsogiannisLab
📢New preprint: We elucidated the structure of the peroxisomal Pex1/Pex6 ATPase complex processing an endogenous substrate. Kudos @RuetterM and all co-authors. #cryoEM #peroxisome #pexophagy @WWU_Muenster #SoN https://www.biorxiv.org/content/10.1101/2022.11.19.517173v1

@ditlevbrodersen This early, some fields have moved significantly (#neuroscience being one of them), others I'm not so sure. One way to discover people in your field is via hashtags: click on them, or even follow hashtags. And use hashtags when writing posts to make them discoverable. I've been using #vEM for volume electron microscopy, and #science or #academia when posting job ads or announcements. And surely #cryoEM exists (yes: shows 25 tagged posts per week at the moment). And see also::

#feditips : for tips on how to use the #fediverse and #mastodon.

We are recruiting group leaders at Sheffield University. Interests can be across the biosciences and can include structural biology such as #cryoEM. Interests in #microbiology subjects related to #AMR are also particularly encouraged. For details https://www.jobs.ac.uk/job/CUV141/lecturer.

RT @PiperProteins
Behind @PiperProteins is an actual scientist & that scientist publishes actual science in @NatureComms 🥳We use #CryoEM and #MD simulations to look at membrane receptors to better understand how these are activated! Stay tuned for more animations https://www.nature.com/articles/s41467-022-34629-3 (1/2)

RT @Barandunlab
Very excited to share our latest published #cryoEM work on the #microsporidian #proteasome with all its proteolytic sites inhibited simultaneously by a PI31-like peptide!! Fantastic job from Nathan, Kai, Rahel, and Dennis, and collaboration with Charlie (@CT_CAES)!

Many thanks to Jan Kosinski for joining #SBGrid in October to introduce us to #Assembline, a new tool for Integrative structural modeling of macromolecular complexes. Watch on https://www.youtube.com/watch?v=XYkDL8Dl-2Q #structuralbiology #cryoem #crystallography #protein #software #massspec #tomography

Another #introduction from someone considering leaving the dark side of the force ... #TwitterMigration

Trained in #cellbiology, I caught fire for all things EM pretty early on, brought #Austria's first dedicated facility using #cryoem to life in 2006, and started my own company Nexperion in 2013.

Now busy with lots of #SerialEM, #cryoem, #cryotomo, and a monitoring system for TEM developed by my company, named Sentinel.

Also: #archlinux, #sweden, ...

We are proud to present #ModelAngelo: a deep-learning based approach to automated model building in #cryoEM maps by the amazing Kiarash Jamali (@jamaliki1998), with help from Dari @kimanius.

https://arxiv.org/abs/2210.00006 https://twitter.com/SjorsScheres/status/1577222658575695876/photo/1

Our #bioRxiv preprint on actin-tropomyosin #cryoEM structures in non-muscle cells with @M__Selvaraj @LabLappalainen @BIOTECH_UH DiMaio Lab @UWBiochemistry👉https://biorxiv.org/cgi/content/short/2022.05.12.491677v1 https://twitter.com/JuhaHuiskonen/status/1525084779128967168/video/1

Substrate translocation in an abc transporter visualized by #cryoEM 👇 https://www.biorxiv.org/content/10.1101/2022.04.28.489897v1 Many thx to @Thgeweri @DJanuliene @MoellerGroup @UniOsnabrueck @MPIbp and twitterless QZhang and IUrbatsch https://twitter.com/krparey/status/1520493734487629828/video/1