#Vaccinated people have lower levels of #inflammatory markers after #COVID19 infection https://www.news-medical.net/news/20230808/Vaccinated-people-have-lower-levels-of-inflammatory-markers-after-COVID-19-infection.aspx “The study published today in The #Lancet Microbe found among individuals recently infected with #SARSCoV2, those who were fully vaccinated had lower concentrations of almost all #inflammation markers (#cytokines and #chemokines) than those who were #unvaccinated in the short-term and long-term after symptomatic SARS-CoV-2 infection.”

Severe #COVID19 may lead to long-term innate #immune system changes

> These findings suggest that #SARSCoV2 can cause changes in gene expression that ultimately boost the production of #inflammatory #cytokines and one type of those cytokines perpetuates the process by inducing these changes in stem cells even after the illness is over.

https://www.nih.gov/news-events/news-releases/severe-covid-19-may-lead-long-term-innate-immune-system-changes

Epigenetic memory of #coronavirus infection in innate immune cells and their progenitors

https://www.cell.com/cell/fulltext/S0092-8674(23)00796-1

#Sars2 #covid19

#cytokines as #biomarkers for therapeutic success in #NSCLC #nsclctrial #Immunotherapy #pd1 #pdl1 utilizing #MachineLearming , link to downloadable PDF https://bit.ly/3NTxfTt

“Researchers have shown that the inflammatory molecule IL-17 has a key function in skin aging. The study was published in Nature Genetics by a team of researchers from the Institute for Research in Biomedicine (IRB Barcelona) working alongside the National Center for Genomic Analysis (CNAG).” #dna #epigenetics #aging #cytokines #geneadons #isogg https://www.technologynetworks.com/immunology/news/blocking-inflammatory-protein-may-delay-skin-aging-374600

#IDMastodon The elevations of IL-10, IL-23, TNF-α levels in severe & critical #COVID19 cases linked to the in-hospital mortality . A prediction model shows that these #cytokines upon admission is important and should be done on COVID-19 patients as a way of evaluating the prognosis of the disease. #COVID19 Patients with high IL-10, IL-23, and TNF-α on admission are more likely to experience a severe form of the disease; therefore, those patients should be cautionary monitored and treated.

Blood-based inflammatory markers in acute vs chronic schizophrenia
https://www.nationalelfservice.net/?p=170315

Éimear Foley summarises a recent meta-analysis, which looks at alteration patterns of peripheral concentrations of cytokines and associated inflammatory proteins in acute and chronic stages of schizophrenia.

#Inflammation #Schizophrenia #Psychosis #CReactiveProteins #Cytokines #Interleukin

Very pleased to see our paper is now in print:
https://www.cell.com/cell-reports/fulltext/S2211-1247(23)00430-8

here we show how RNA binding proteins regulate the magnitude and timing of cytokine expression in human T cells. and how the identified RBPs act a different time points and through different mechansism. The wonder world of RNA...

#RNA #RBPs #Immunology #Tcells #cytokines #regulation #proteomics

When the immune system attacks the immune system: #Autoantibodies against #interferons (type I) have an impact on #immuneresponses and are associated with viral disease susceptibility as outlined in this elegant review... #immunology #virology #cytokines #infections #autoimmunity #immunoregulation
https://onlinelibrary.wiley.com/doi/abs/10.1002/eji.202250164

“The extensive co-localization data supports the hypothesis that the #SpikeProtein per se concentrates in cells in the interstitium of the #heart, likely through migrating #macrophages and pericytes, which are activated and express pro-inflammatory #cytokines.”

“the primary and novel finding of this study is that there is substantial in situ expression of #cytokines and #complement activation in the heart secondary to #endocytosis of circulating spike proteins by cardiac interstitial #macrophages and pericytes which, in turn, induces a #myocarditis. “

#macrophages can be selectively modulated through #cytokines : #CCR5 and CCR1 mediates re-polarization. #innateimmunity in Action for #Immunotherapy in #cancer
https://jitc.bmj.com/content/10/1/e003131

Signed up for a dissection class Friday afternoon prior to our #repoductivebiology practical. We get to dissect rat testes. This makes me giddier than it probably should.

Also, even though the wiki project for our #cancer #immunotherapy project is very messed up, I stepped up and claimed #cytokines as my section to complete.

See I am trying to be a good #student

#medicalscience #edinburghuniversity aiming for #scotgem 🤞🏻

This March the Dutch Society for Immunology (DSI/NVVI) host the NVVI Spring Meeting. We host inspiring talks on many topics in #immunology: #Infection, #Modeling, #Neuroscience, #Cytokines, #TumorImmunology.
It's a relatively small meeting, so you have plenty of opportunities to meet the speakers and other participants.

Early bird registration ends February 16th.

More information:
https://www.nvvi-dsi.nl/events2/sring-symposium-2023

Nous n'avons trouvé aucune différence majeure au niveau du #microbiote #vaginal et de légères différences dans les profils #immunitaires.

Pour plus de détails sur les profils de #cytokines, voire cet article : https://doi.org/10.1007/s12026-021-09196-2

5/N

Just read 3 papers in bed on pDCs, plasmacytoid dendritic cells. Now I'm pondering IL-1 action in #cytokines, and what happens in people without lymph nodes with SARS COV2 vs. someone with low pDCs post #covid infection, and the presentation of #lupus.

It's 12:30 at night, I'm an #insomniac that needs sleep and my job description is "#guitar teacher".

I'm doing "this" wrong, I know. Sigh.

Nasal Spray Vaccine Shown to Stop Gonorrhea Infections

A #vaccine against #gonorrhea given as a nasal spray is shown to generate protective #immune responses in lab mice of both sexes, and in females similar to an intravaginal vaccine.

https://sciencebusiness.technewslit.com/?p=44337

#News #Science #Business #NasalSpray #STD #Bacteria #GramNegative #Preclinical #Biotechnology #Chemistry #Cytokines #Formulation #Collaboration

In this Future Leader Review, Angie Yu Ching Poon and @rio_sugimura review recent progress in natural killer cells for #cancer #immunotherapy:

https://journals.biologists.com/bio/article/11/12/bio059396/284640/The-prospect-of-genetically-engineering-natural

Find out more how to propose your own Future Leader Review here:

https://journals.biologists.com/bio/pages/reviews

#Cytokines #Disease #Biology #BiologyOpen #Science #AcademicMastodon

Y otra vez casualmente vengo de correr 6 kilómetros y me siento doblemente mejor.

RT @KulikovUNIATF@twitter.com

Benefits conferred by regular #exercise to overcome #obesity are attributed not only to reduced adiposity or reduced levels of circulating lipids but also to #cytokines - proteins, peptides, enzymes & metabolites released from 💪🏽 muscle or other organs. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145589/

🐦🔗: https://twitter.com/KulikovUNIATF/status/1614288450814869504

Y otra vez casualmente vengo de correr 6 kilómetros y me siento doblemente mejor.
---
RT @KulikovUNIATF
Benefits conferred by regular #exercise to overcome #obesity are attributed not only to reduced adiposity or reduced levels of circulating lipids but also to #cytokines - proteins, peptides, enzymes & metabolites released from 💪🏽 muscle or other organs. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145589/
https://twitter.com/KulikovUNIATF/status/1614288450814869504

Nanotech Enzyme Process Boosts T-Cell Cancer Therapies

A #bioengineering team devised techniques for feasibly adding cancer-killing #enzymes to engineered #immune cells that in lab mice kill solid #tumor and blood #cancer cells.

https://sciencebusiness.technewslit.com/?p=44317

#News #Science #Engineering #Biotechnology #Chemistry #ClickChemistry #Nanotechnology #Cytokines #Preclinical #University