Muninn 🍃 · @muninn
336 followers · 2730 posts · Server social.coopOho, there's a proprietary genetic test which predicts #desvenlafaxine (#Pristiq) dose quite well in an early study! Let's see if I can replicate it with 23andme raw data. I'd be doing a lot more stuff like this if I were less depressed... off to sci-hub! #diypsychiatry #diy
Concordance between actual and pharmacogenetic predicted desvenlafaxine dose needed to achieve remission in major depressive disorder
https://www.ncbi.nlm.nih.gov/pubmed/27779571
#desvenlafaxine #pristiq #diypsychiatry #diy #pharmacogenetics
Muninn 🍃 · @muninn
336 followers · 2730 posts · Server social.coopMy #antidepressant (#desvenlafaxine aka #Pristiq) is a #phenethylamine. That's rare. It shares that skeleton with other big names like #MDMA, #mescaline, and #Sudafed.
It's a #SSNRI, blocks #serotonin reuptake 5-10x more strongly than #norepinephrine, and may increase #dopamine turnover in the prefrontal cortex.
It has some subjective aspects quite reminiscent of #phenethylamines I've tried.
#antidepressant #desvenlafaxine #pristiq #phenethylamine #mdma #mescaline #sudafed #ssnri #serotonin #norepinephrine #dopamine #phenethylamines #drugs #pharma #pharmacology #antidepressants