The sorry of the discovery of the structure of DNA is complicated, and our understanding incomplete. On #DNADay23 read this thread, unravelling the twin contributions of King's and Cambridge
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RT @matthewcobb
70 years ago, 3 papers appeared in @Nature under the title ‘Molecular structure of nucleic acids’. In an article in Nature today (link at end) @nccomfort and I shed new light on ‘what Watson and Crick really took from Rosalind F…
https://twitter.com/matthewcobb/status/1650877644529975296

5/5 Solving the mystery of DNA rings: Anton Henssen (@anton_gh, #mdcberlin & @ChariteBerlin) and scientists from 🇺🇸 and 🇬🇧 research the role that ring-shaped strands of DNA play in the development of #cancer, and how to fight them.

https://www.mdc-berlin.de/news/press/cancer-grand-challenge-henssen

#DNADay #DNADay23

4/5 Antibodies can "steal" pieces of other #genes: Kathrin de la Rosa (@berlinnovation) analyzes how the body creates a diverse set of #antibodies to fight off #infections. Her team reports: It's not just mutations @PNASNews

https://www.mdc-berlin.de/news/press/stolen-dna-strengthens-immune-diversity

#DNADay #DNADay23

3/5 Abnormalities in DNA folding presumably cause learning disorders. Ana Pombo (@apombo1 / @BIMSB_MDC) and Alexander Kukalev have received a @dfg_public grant to test this hypothesis.
https://www.mdc-berlin.de/news/news/cracking-chromatin-code

#DNADay #DNADay23

2/5 The fins of skates: The key to their #evolution lies in the non-coding bits of the animals’ #genome and the 3D complexes it folds into: TADs. #mdcBerlin scientist @Dariloops (@BIMSB_MDC) is among the lead authors of the @Nature paper.
https://www.mdc-berlin.de/news/press/how-skates-learned-fly-through-water
#DNADay #DNADay23

🧬 #DNA sequencing technologies on a European level: On May 4, the @EasiGenomics Summit in Berlin will be a grand finale for the project!

Janine Altmüller (#mdcBerlin & @berlinnovation) is talking about the past 4 years: https://www.mdc-berlin.de/news/news/grand-finale-european-genome-project

#DNADay #DNADay23

n honor of #DNADay23, please consider the many accomplishments of pioneering scientist Rosalind Franklin (1920 - 1958).

During her distinguished career, Franklin carried out ground-breaking research into coal and viruses but she is perhaps best remembered for her investigations in the field of DNA. Franklin was a world-class X-ray crystallographer, physical chemist and experimentalist, and in May of 1952 her student Raymond Gosling made the famous Photograph 51, which is the nickname given to an X-ray diffraction image which clearly shows the double-helix structure of DNA (see the image below). Gosling was working as a PhD student under the supervision of Rosalind Franklin at King's College London in Sir John Randall's group, though apparently Randall saw it differently (not surprisingly, Randall thought that he was supervising Franklin and hence Gosling).

Watson and Crick used Photograph 51 to help deduce the double-helix structure of DNA, one of the most important discoveries of modern science. The backdrop of this discovery was complex: there were all kinds of issues here, like the competition between Kings (where Franklin was) and Cambridge (where Watson and Crick were); being a woman in science, and the fact Kings was working on dehydrated forms of DNA (A-type) while Photograph 51 was B-type (it seems researchers at Kings were looking at A-type while researchers at Cambridge were looking at B-type). Nevertheless, Franklin's notebooks contained all of the measurements of Photograph 51 (and others) which clearly showed the double-helix structure of DNA as well as other properties.

Hoy se cumple el 70 aniversario del descubrimiento del ADN. Me sorprende constantemente el progreso que los investigadores están logrando con el uso de Oxford Nanopore. Es vivir en un sueño de relaísmo mágico. ¡¡Vamos a los próximos 70 años! #DNADay23 @Pore_XX

Today is the 70th anniversary of DNA. I'm constantly surprised by the progress that researchers make on a daily basis using ONT. My job feels like living inside a magical realism waking dream. What will the next 70 years unlock!?!

RT @genome_gov
Celebrate #DNADay23 by making some DNA origami! It’s a fun and creative way to learn about the double helix. http://genome.gov/DNAorigami