I have a PhD in molecular biology (DNA stuff)
I work for a company that makes stuff for cutting edge DNA sequencing

I assert: most of the new hi tech stuff one sees in academic journals (eg, "Analytical Chemistry" , "Lab on a Chip") is pretty useless from a practical POV, even tho the authors make extravagant claims about real world utility

#DNA #RNA #Proteins #Genomics #DNASequencing #BioTech #Science #STEM #CuttingEdge

AAAS: "Air pollution sensors can double as biodiversity monitors." Study demonstrates an inexpensive way to sniff out species from 'environmental' or eDNA snagged in air filters. “We are starting to see [that] eDNA is left everywhere,” says Kristine Bohmann, a molecular ecologist at the University of Copenhagen. 'Larger animals slough off DNA in skin, scales, and feathers, and researchers have also detected eDNA from mussels, sponges, dung beetles, spiderwebs, and even carnivorous plants, on land and in water.' Bohman + other research teams have also shown they can find DNA from plants, insects + mammals. "Samples included DNA from threatened species such as hedgehogs and songbirds; ash, linden, and oak trees; and crops such as wheat and cabbage." If old filters are kept dry, the DNA is stable. Per Stenberg, a geneticist at Umeå University 'examined DNA from 30 years’ worth of archived air filters, removed weekly from sensors set up to detect radioactive fallout from nuclear explosions across Sweden.' In theory, documentation of biodiversity could prompt greater efforts to maintain it. Lots of intriguing possibilities. Some a bit worrisome. #dnasequencing #monitoringsystem #biodiversity

#DNA #biology #DNASequencing #Computers #HardDrives #SSD
I actually know about DNA sequencing
If you had a time machine, and delivered blueprints for a DNA sequencer and all the associated stuff back to 1990, or maybe even 1985, scientists would have had no trouble at all making a modern DNA sequencer except for one issue:

The cost of computers, and hard drives, was so high that the sequencer would have cost a NASA level fortune to run

why ?
a DNA sequencer spews out tera bytes of dat/day

https://www.cam.ac.uk/stories/beethovens-dna-reveals-health-and-family-history-clues

Scientists have sequenced Ludwig van Beethoven’s genome from locks of his hair, revealing clues to the great composer’s health and his family history. The study's lead author, Tristan James Alexander Begg, from the Cambridge Department of Archaeology and Clare Hall, University of Cambridge, explains how they did it and what they discovered.

#beethoven #DNASequencing #CambridgeUniversity

Cheaper gene screening makes for DNA data dilemma
#Science #Health #GeneScreen #Genetics #DNA #DNASequencing #SDG10 #SDG3 #DNAData #Genes #DNADataBenefits #Data #Dilemma
https://the-14.com/cheaper-gene-screening-makes-for-dna-data-dilemma/

The race to improve DNA sequencing
#DNA #DNASequencing #Economy #Health #Science #Technology #Environment #Agriculture #Biotechnology #Chemicals #People #Population #SDG10 #SDG3 #Software #MedicalResearch #Illness #MedicalConditions #GeneScreen
https://the-14.com/the-race-to-improve-dna-sequencing/

This is my #Introduction post!

Once per day, I generate a random #DNA sequence position weight matrix and draw a sequence logo based on it.

Please follow, favorite, and boost if you like DNA logos, #bioinformatics, #genomics, or just #MolecularBiology in general!

#Molecular #Biology #MolecularBio #DNASequence #DNASequencing

When I started #DNAsequencing, I was manually reading A,C,G and T as individual bands on an autoradiograph of a sequencing gel (#SangerSequencing)...

Now this new tool offers a universal sequencing read interpreter...

New research in Science Advances on:

https://www.science.org/doi/10.1126/sciadv.add2793

#genomics #bioinformatics #sequencing

What's the best way to preserve and store cat fur for future DNA verification/comparison? I figure if I save cat fur samples that's the most reliable way to authenticate my acrylic and oil paintings later on. 😆

*currently being purred and shed on* #StudioCats #DNASequencing #CatDNA #ArtAuthentication #DNAPreservation #ArtProvenance

#DNA #genomics #genetics #dnasequencing

Your reminder that although we do have in fact a nearly complete* DNA sequence for a few people, our knowledge of what the sequence means is *very incomplete

*one of the biggest myths of the popular science press is that the human genome was sequenced back in 2000
In fact, we only got a complete (or nearly complete, iirc, the rRNA repeats are not yet sequenced fully) in the last year or so with the PacBio HiFi technology

Happy to see the @nf_core #methylseq pipeline being put through its paces for this article! 🚀

Don't believe the results? Download the raw data and run the workflow yourself 😁🧑‍💻
---
RT @ElemBio
Learn how we assessed AVITI's capability with MethylSeq libraries in this brief blog article and then download the FASTQ sequencing datasets to check them out for yourself! https://bit.ly/3ETs2qu

#dnasequencing #genomics #sciencecantwait
https://twitter.com/ElemBio/status/1598469048479653890

#TibetanDNA #Tibet #DNAsequencing #ThermoFischer

In 2019 Thermo Fisher stopped selling DNA sequencing kits in Xinjiang. But 2022 and they are selling to the police in Tibet.

https://theintercept.com/2022/09/13/china-tibet-police-dna-thermo-fisher/

This is nice. Using bees, which naturally collect pollen and material from a wide area, as natural plant disease detectors.

"By sequencing genetic material from the bees’ bodies or from the pollen they deposit in the hives’ honeycomb, Roberts’s team has been able to verify the presence of known plant diseases. They have even detected one that hasn’t been officially found in the field: tomato ringspot virus"

https://www.hakaimagazine.com/news/australias-plant-virus-sting-operation/

#Plants #Bees #DNASequencing #Environment

Fascinating.

"The ancient birch gum in Scandinavia preserved enough DNA to reconstruct the full human genome of its ancient chewer, identify the microbes that lived in her mouth, and even reveal the menu of a prehistoric meal."

#Genetics #Prehistory #Europe #DNASequencing

https://www.smithsonianmag.com/science-nature/human-genome-recovered-5700-year-old-chewing-gum-180973801/

What DNA sequencing reveals about commercially sold seafood in Singapore:

"Cuttlefish and prawn balls repeatedly contained pig DNA and 100% of all mixed samples labelled as containing crustaceans ('crab', 'prawn', 'lobster') only yielded fish barcodes."

#DNA #DNASequencing #Singapore #Food

https://www.biorxiv.org/content/10.1101/826032v1

#biology #reptiles #lizards #DNASequencing #KomodoDragon An article published in the journal "Nature Ecology & Evolution" reports a complete genome sequencing of the Komodo dragon, the largest lizard existing today. https://english.netmassimo.com/2019/08/03/komodo-dragon-dna-sequenced