Carlos Cortez shows how a single mutation was sufficient to evolve Hb from a tetramer to a dimer. How does specificity of heterotetramer evolve? 2 deletions and 1 substitution in one of the 2 paralogs are sufficient. Overall, evolving heterotetramer complex from identical at birth paralogs is remarkably simple. #SMBE2023 #paralog #duplication
#smbe2023 #paralog #duplication
Announcing #SIB Comparative genomics course, taught by Christophe Dessimoz, Natasha Glover, @rmwaterhouse and myself, 30 August - 01 September in Lausanne #UNIL
• Introduction to molecular evolution & phylogenetics
• Orthology-focused arthropod comparative genomics
• Duplication of genes and genomes, expression
with #SIB resources #OMA, #Orthodb #BUSCO and @bgeedb #ortholog #orthologs #paralog #duplication #MolecularEvolution #Genomics #bioinformatics #training @P_Palagi https://www.sib.swiss/training/course/20230830_COMGE
#SIB #UNIL #oma #orthodb #busco #ortholog #orthologs #paralog #duplication #MolecularEvolution #Genomics #bioinformatics #training
#Aneuploidies are an ancestral feature of #trypanosomatids, and an ancient chromosome #duplication is maintained in extant species
João Luís Reis-Cunha et al
bioRxiv 2023.06.26.546280; doi: https://doi.org/10.1101/2023.06.26.546280
#aneuploidies #trypanosomatids #duplication #leishmania #genome #genomics #aneuploidy
Japanese navy? Nah, just an #OpticalIllusion! Or is that what they'd want us to think?? 🙄 The second image shows #sunspots better. Taken seconds apart. Today's #sunset produced a bit cleaner red hues, the air seems cleaner, too.
#Phantom #Projection #Duplication #Reflection #Silhouette #Photography #Castle #Tower #EarlierToday #FensterFreitag (on a Sunday) #Urban #Landscape #Cityscape #Canon #600mm #Soligor #VintageLens #Vivitar #Teleconverter #SooC #NoFX #Unprocessed #SlowAperture #Handheld #IBIS
#opticalillusion #sunspots #sunset #phantom #projection #duplication #reflection #silhouette #photography #castle #tower #earliertoday #Fensterfreitag #urban #landscape #cityscape #canon #600mm #soligor #vintagelens #vivitar #teleconverter #sooc #nofx #Unprocessed #slowaperture #handheld #ibis
Double #Sunset, take two. Or is it a #VennDiagram? #Boolean NOT maybe? 🎴
#Phantom #Projection #Duplication #Reflection #Silhouette #Photography #Castle #Tower #JustNow #FensterFreitag (on a Saturday) #Urban #Landscape #LandscapeInPortrait #Cityscape #Canon #135mm #Konica #Hexanon #VintageLens #Kenko #Teleconverter #SooC #NoFX #Unprocessed #SlowAperture #Handheld #IBIS
#sunset #venndiagram #boolean #phantom #projection #duplication #reflection #silhouette #photography #castle #tower #justnow #Fensterfreitag #urban #landscape #landscapeinportrait #cityscape #canon #135mm #konica #Hexanon #vintagelens #kenko #teleconverter #sooc #nofx #Unprocessed #slowaperture #handheld #ibis
Double #Sunset! #Phantom #Projection #Duplication #Reflection #Silhouette #Photography #Castle #Tower #JustNow #FensterFreitag (+1 😜) #FensterSamstag #Urban #Landscape #Canon #135mm #Teleconverter #VintageLens
#sunset #phantom #projection #duplication #reflection #silhouette #photography #castle #tower #justnow #Fensterfreitag #fenstersamstag #urban #landscape #canon #135mm #teleconverter #vintagelens
As the system began to get bogged down, engineers began building their own solutions. This not only duplicated efforts but also led to more code to maintain and a bigger surface for potential issues, which led to a higher volume of alerts.
https://engineering.fb.com/2020/08/17/production-engineering/async/
Tolerating, then Eliminating #Duplication at #Amazon
https://pedrodelgallego.github.io/blog/amazon/tolerating-eliminating-duplication/
November issue of Evolutionary Applications is online:
https://onlinelibrary.wiley.com/toc/17524571/2022/15/11
16 relevant contributions investigating #AppliedScience from the point of view of #Evolution
a bit of everything for all tastes: #genomes #communities #bacteria #species #adaptation #cancer #duplication #fish #plants #tree #insect #Oyster #genomics
#AppliedScience #Evolution #genomes #communities #bacteria #species #adaptation #cancer #duplication #fish #plants #tree #insect #Oyster #Genomics
#theconversation #science "La duplication du génome : facteur de résistance aux traitements des cancers" #génome #duplication #santé #cancer #ADN #chromosome ... https://theconversation.com/la-duplication-du-genome-facteur-de-resistance-aux-traitements-des-cancers-168103
#theconversation #science #génome #duplication #santé #cancer #adn #chromosome
#theconversation #science "La duplication du génome : facteur de résistance aux traitements des cancers" #génome #duplication #santé #cancer #ADN #chromosome ... https://theconversation.com/la-duplication-du-genome-facteur-de-resistance-aux-traitements-des-cancers-168103
#chromosome #adn #cancer #santé #duplication #génome #science #theconversation