A #model thats keeps #giving even after #90years "Experimental Allergic encephalomyelitis" #EAE @JExpMed https://rupress.org/jem/article-abstract/220/2/e20221322/213807/Experimental-encephalomyelitis-at-age-90-still/

Es intolerable el comportamiento autocrático del Ministerio de Agricultura al respecto del #PEPAC

¿De qué sirve la #eae si en la práctica no tiene efecto?

El proceso de participación se podría situar entre la manipulación y la terapia
#PAC

https://elpais.com/economia/2022-12-29/ribera-y-planas-chocan-por-el-plan-estrategico-de-la-pac.html

Venous #EndothelialCell as #Angiogenesis origin in🐭#EAE #MultipleSclerosis

Blocking VEGFA (Bevacizumab 7 dpi)
⏬Aberrant angiogenesis
⏫Myelination+neuromotor
BUT w/o altering Immune cell infiltration or Endothelial Barrier (IgG)😎
Dr. Dritan Agalliu lab bioXRiv 2022
https://www.biorxiv.org/content/10.1101/2022.11.15.516660v1

"Using the CD4+ T cell-mediated disease experimental autoimmune encephalomyelitis (EAE), we show here that this process is markedly suppressed when TLR9 signaling is increased, without noticeably affecting the transcriptome of primed T cells, indicating a purely quantitative effect on CD4+ T cell expansion."

#Immunology #TLR #eae

https://onlinelibrary.wiley.com/doi/abs/10.1002/eji.202250059

#EndothelialCell ARF6 GTPase links IL-1β inflammation with TGFβ/BMP-SMAD1/5 #EndMT

EC Arf6 KO in🐭#EAE->
⏫#BBB #BloodSpinalCordBarrier
⏬T cell infiltration & demyelination
w/o altering normal immunity

Dr. Shannon Odelberg, Weiquan Zhu labs Neuron 2022
https://www.sciencedirect.com/science/article/pii/S0896627322006602

#HauteskundeSindikalak
#ZureBideLagun
#EAE #Justizia

BALORAZIOA: 2019ko hauteskundeak: indarberritu gara
🔗 https://labur.eus/FqMNG

(Zuzenketa)
#ZureBideLagun #HauteskundeSindikalak
#Justizia #EAE

LAB 11 ⬆️
ELA 17 ⬆️
CCOO 15 ⬇️
CSI-F 9 ⬇️
CGT 2 ⏸

ZORIONAK LAB!!!

#ZureBideLagun #HauteskundeSindikalak

#Justizia #EAE

LAB 11 ⬆️
ELA 17 ⬆️
CCOO 15 ⬇️
CSI-F 11 ⬇️
CGT 2 ⏸