Hi #ScienceMastodon, I'm happy to share with you the last Research Highlight from JCS Issue 15. Paul Gleeson and colleagues from the University of Melbourne and Rheinische Friedrich-Wilhelms-Universität Bonn use blood outgrowth endothelial cells to map out the intracellular trafficking route of human serum albumin.
#CellBiology #vascularbiology #endocytosis
A rapid recycling route rescues HSA from degradation
#sciencemastodon #cellbiology #vascularbiology #endocytosis
Postdoctoral Positions in Plant Proteostasis
RWTH Aachen University
Postdoctoral Positions in Plant Proteostasis to study #ubiquitinsignalling #endocytosis #targetedproteindegradation at the @RWTH in the @TrujilloLab
See the full job description on jobRxiv: https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis/?feed_id=52035
#Science...
https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis/?feed_id=52035
#science #targetedproteindegradation #endocytosis #ubiquitinsignalling
Postdoctoral Positions in Plant Proteostasis
RWTH Aachen University
Postdoctoral Positions in Plant Proteostasis to study #ubiquitinsignalling #endocytosis #targetedproteindegradation at the @RWTH in the @TrujilloLab
See the full job description on jobRxiv: https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis/?feed_id=50851
#Science...
https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis/?feed_id=50851
#science #targetedproteindegradation #endocytosis #ubiquitinsignalling
“the primary and novel finding of this study is that there is substantial in situ expression of #cytokines and #complement activation in the heart secondary to #endocytosis of circulating spike proteins by cardiac interstitial #macrophages and pericytes which, in turn, induces a #myocarditis. “
#cytokines #complement #endocytosis #macrophages #myocarditis
This new paper from Obashi and colleagues in the Taraska lab is very nice. It uses a FRET-CLEM approach to look at protein conformations in cells and tie those to ultrastructural correlates. Here they are looking at clathrin light chain dynamics relative to the clathrin cage during #endocytosis, but there are many other questions in cell biology where this could be applied.
https://doi.org/10.1038/s41467-023-36304-7
#CellBiology #StructuralBiology #ElectronMiscroscopy #MembraneTraffic
#endocytosis #cellbiology #structuralbiology #electronmiscroscopy #membranetraffic
RT @FitzpatrickLab
Excited to share the structural basis of pH-activated #endocytosis by LRP2 using #cryoem now online @cellcellpress:
Great collaboration with Andrew Beenken @theGABcerutti Jonathan Barasch @ColumbiaKidney @lawrenceshapiro @ZuckermanBrain @ColumbiaBiochem
#Parasitology #preprint: new from Drew Etheridge lab (FA: N.Chasen
) looking at role of #myosins in #Tcruzi #endocytosis. Show MyoF+MyoC in complementary roles & also ID an essential new protein (MyAP) required for their targeting to the SPC🤩👍👏
#preprint #parasitology #myosins #Tcruzi #endocytosis
RT @DomenicoAzTe
Keep CALM and don’t forget to attend this Thursday at 5pm (Berlin time) the next Membrane seminars! Looking forward to talk about #endocytosis, #neurons, #synapticplasticity and #AlzheimersDisease! 😉 https://twitter.com/fran_bottanelli/status/1592153152823988225
#endocytosis #neurons #synapticplasticity #alzheimersdisease
Twitter (and #mastodon) #cellbio #membrane community! Membrane seminars are back this Thu 5 pm (Berlin/Barcelona time). This week a bit of #neuron and #endocytosis with @DomenicoAzTe from @VolkerHaucke's lab and #Rab #GTPases #mitosis with Stéphanie Miserey @institut_curie!
#Mastodon #cellbio #membrane #neuron #endocytosis #Rab #GTPases #mitosis
#Micro #filaments are usually about 7 nm in #diameter and #made up of #two #strands of #actin. Microfilament #functions #include #cytokinesis, #amoeboid #movement, #cell #motility, #changes #in #cell #shape, #endocytosis and #exocytosis, #cell #contractility, and #mechanical #stability. #Microfilaments are #flexible and #relatively #strong, #resisting #buckling by #multi #piconewton #compressive #forces and filament #fracture by #nanonewton #tensile #forces.
#tensile #nanonewton #fracture #Forces #compressive #piconewton #multi #buckling #resisting #strong #relatively #flexible #Microfilaments #stability #mechanical #contractility #exocytosis #endocytosis #shape #in #changes #motility #cell #movement #amoeboid #cytokinesis #include #functions #actin #strands #two #made #diameter #filaments #micro