The EMBO Journal · @embojournal
424 followers · 136 posts · Server sciencemastodon.com
Antitumor T-cell function requires #CPEB4-mediated adaptation to chronic #endoplasmic #reticulum stress
Raúl Méndez and colleagues at IRB Barcelona show that RNA-binding protein CPEB4 mediates transient unfolded protein response #UPR for stress adaptation in #CD8 #Tcells
#cpeb4 #endoplasmic #reticulum #upr #cd8 #Tcells
CellBioNews · @cellbionews
25 followers · 537 posts · Server scientificnetwork.deResearchers reveal #endoplasmic reticulum–associated #protein degradation and control of grain size in #rice.
#agriculture #ubiquitin #proteasome
https://phys.org/news/2023-02-reveal-endoplasmic-reticulumassociated-protein-degradation.html
#endoplasmic #protein #rice #agriculture #Ubiquitin #proteasome
The EMBO Journal · @embojournal
312 followers · 39 posts · Server sciencemastodon.com
A link between #Smoothened #cholesterylation and #endoplasmic #reticulum exit in #Hedgehog signaling: #GRAMD1-mediated #cholesterol transfer and Smoothened modification accelerates it #COPII-dependent ER exit and promotes signaling
https://www.embopress.org/doi/10.15252/embj.2022111513
#smoothened #cholesterylation #endoplasmic #reticulum #hedgehog #gramd1 #cholesterol #copii