elevated #vascular #endothelial cell turnover and #erythropoiesis in #asymptomatic #COVID19 patients | https://www.biorxiv.org/content/10.1101/2023.07.28.550957v1 “Asymptomatic patients had elevated levels of immune-derived cfDNA but did not show evidence of #pulmonary or #cardiac damage. Surprisingly, these patients showed elevated levels of vascular endothelial cell and erythroblast cfDNA, suggesting that sub-clinical vascular and erythrocyte turnover are universal features of COVID19, independent of disease #severity.

Gene Expression: How their environment influences #endothelial cells. https://elifesciences.org/articles/88248?utm_source=mastodon&utm_medium=social&utm_campaign=organic_insights

Blood endothelial #ALK1-#BMP4 signaling axis regulates adult hair follicle #stemcell activation
Kefei Nina Li, Doina Tumbar et al

Blood vessel #endothelial cells form a #quiescence-inducing signaling niche for skin stem cells

https://www.embopress.org/doi/10.15252/embj.2022112196

What happens downstream of transcription factor #Prox1 during #transdifferentiation of embryonic venous #endothelial cells (VECs) into #lymphatic endothelial cells (LECs)?

Benjamin Hogan and colleagues use #singlecell profiling to reveal regulation of early events in #zebrafish #lymphangogenesis

https://www.embopress.org/doi/10.15252/embj.2022112590

@RKI

#SarsCov2 is intrinsically virulent, it's a multiorgan disease

https://ec.europa.eu/eurostat/statistics-explained/index.php?title=Weekly_death_statistics&stable

#endothelial tissues of any infected person is indangered every single time of infection

EVERYBODY is vulnerable once ... life expentance is dropping down continously

#COVIDisAirborne
#covidisnotover

⤵️
https://doi.org/10.1182/blood.2021012250

"Due to widespread #endothelial dysfunction and thrombosis, #COVID19 has the ability to affect nearly any organ. Pulmonary disease, specifically ARDS, may be driven in large part by vascular dysfunction & #microvascular thrombosis. Increased thrombotic events, most notably venous #thromboembolism but also myocardial infarction and stroke, have been reported. Vascular dysfunction may contribute #neurologic, renal & dermatologic manifestations
as well as #pacs & #misc "

“the heart has a large endogenous population of #macrophages and pericytes that are in direct contact with the #endothelial cells of microvessels which may offer a defense mechanism to rapidly deal with systemically borne pathogens. A key finding of this study, documented by other investigators, is that these cells, as well as endothelial cells, strongly express #ACE2 in the #cardiac tissues”

Origin of #endothelial #cells constituting the vascular niche for hematopoietic stem and progenitor cells in #zebrafish.

#HSPCs

https://phys.org/news/2023-01-endothelial-cells-constituting-vascular-niche.html

#Ebola virus disrupts the inner #blood-retinal #barrier by induction of vascular #endothelial growth factor in pericytes https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011077

RT @GoetzJacky
🔥🎄 Christmas paper alert🎄🔥
Have you ever wondered how and whether fluids that transport #extracellularvesicles impact their fate ?
We did and we now show that blood flow diverts EVs from #endothelial degradative compartments to promote #angiogenesis 🧵
https://www.biorxiv.org/content/10.1101/2022.12.19.521008v1

Working with one eye as I recover from my cornea transplant. The gas bubble in my eye is helping to adhere and graft the donor tissue. Laying flat with eyes up for several hours per day allows the bubble to be centered, providing full coverage of the donor tissue. Vision in the new eye is extremely blurry due to the bubble but I see light and am optimistic for when the gas dissipates.

#surgery, #endothelial, #keratoplasty, #cornea, #transplant, #DMEK, #fuchs, #dystrophy, #ophthalmology

Going uner the knife tomorrow morning for a cornea transplant to treat Fuchs' Dystrophy. Grateful for modern medicine.

#surgery, #endothelial, #keratoplasty, #cornea, #transplant, #DMEK, #fuchs, #dystrophy, #ophthalmology

RT @endothelialnews@twitter.com

😮 A must-read article about cell-cell contact ☎️ in @ScienceMagazine@twitter.com!

Researchers find that #endothelial cells in the developing heart were genetically labeled after contact with neighboring #cardiomyocytes.

✨ More interesting results here: https://bit.ly/3h2qm5U

🐦🔗: https://twitter.com/endothelialnews/status/1598789626256191489

@mathew1927 @DocMCohen
doubt many people actually do, catching this #endothelial damaging disease that #lurks #hiding in your body for months… over & over #reinfection is stupid beyond belief when you have the #wherewithal to #minimize your #risk
But this #youDoYou BS will never do
Those of us who are #cautious are like the #singular person carrying the entire #groupProject

#tbh I fared exceptionally well & it’s probs due to my current hatred of exercise