jobRxiv · @jobRxiv
954 followers · 3116 posts · Server mas.to
Dan Bose · @danbose
174 followers · 15 posts · Server biologists.social

Fantastic and important paper on function highlighting Alu repeats in and uaRNAs as drivers of –promoter selectivity and linking to non-coding disease risk variants. Lovely work!!nature.com/articles/s41586-023 (apologies if there's a paywall)

#erna #ernas #enhancer

Last updated 1 year ago

Dan Bose · @danbose
173 followers · 13 posts · Server biologists.social

Super work on - contacts; nice role for in maintaining contacts to promoter bursting too! nature.com/articles/s41588-023

#enhancer #promoter #erna

Last updated 1 year ago

Paco Velobs · @PacoVelobs
178 followers · 4098 posts · Server mamot.fr
Paco Velobs · @PacoVelobs
173 followers · 4043 posts · Server mamot.fr
MuSociety(Bam Dorner):flute: · @MuSociety
120 followers · 646 posts · Server musicians.today
Amadeus Paulussen · @amadeus
99 followers · 631 posts · Server mstdn.social
MuSociety(Bam Dorner):flute: · @MuSociety
109 followers · 618 posts · Server musicians.today

TAL-Vocoder by TAL Software FREE

TAL-Vocoder is a vintage-style vocoder with 11 bands that produces the sound of vocoders from the early 80’s. We mixed analog-modeled components and usability with digital algorithms to create an outstanding vocoder so

testblog.music-society.de/tal-

#analog #classic #clean #digital #enhancer #free #harmonic #mono #osc #saw #sidechain #stereo #talsoftware #vintage #vocoder #voice #waveforms

Last updated 2 years ago

Epigenetics Podcast · @epigenetics_pod
318 followers · 110 posts · Server podcasts.social

Nice work of @ElisaKre out of the @arnaud_kr lab. The study shows the intricate relationship between DNA methylation and regulation and reveals that most enhancers are not instructed by 5mC. Yet, methyl-sensitive enhancers are highly dependent on TET activity.

sciencedirect.com/science/arti

#enhancer #epigenetics

Last updated 2 years ago

Aled Parry · @aledjohnparry
92 followers · 16 posts · Server genomic.social

I'm really excited to share our containing a big chunk of my work in the Reik Lab at the Babraham Institute.

We wanted to understand how and oxidation affect the landscape and as exit .

biorxiv.org/content/10.1101/20

#preprint #postdoc #DNAmethylation #enhancer #geneexpression #escs #pluripotency #genomics #PhD #AcademicMastodon #paper #DevBio

Last updated 2 years ago

Robert Castelo · @robertclab
55 followers · 58 posts · Server genomic.social

RT @Julien_Pontis
Primate-specific transposable elements shape transcriptional networks during human development.
nature.com/articles/s41467-022

#TransposableElements #development #gastrulation #stemcells #enhancer #evolution #primates

Last updated 2 years ago

Timothy En Haw Chan · @timchan
53 followers · 5 posts · Server genomic.social

I am Timothy En Haw Chan, a PhD student at University of Freiburg Hospital 🇩🇪 & affiliated with IMPRS-IEM, Max Planck Institute of Immunobiology and Epigenetics. Previously from 🇲🇾 & trained in 🇹🇼. I using to understading landscape, regulators and in . Other interests include mechanism, and . In my spare time, most likely I am writing + editing for science comm (investigator.tw), running 🏃 or hiking ⛰️.

#introduction #omics #epigenetics #chromatin #signaling #cancer #transcription #enhancer #synbio

Last updated 2 years ago

Thiago Carvalho · @cyrilpedia
638 followers · 625 posts · Server qoto.org

"A major challenge is that relatively few enhancers are functionally characterized in vivo, making it difficult to draw generalized conclusions about enhancer-promoter looping during developmental gene activation. Here, we investigate the 3D conformation of enhancers during mammalian development by generating high-resolution tissue-resolved contact maps for nearly a thousand mammalian enhancers with known in vivo activities in ten murine embryonic tissues. We performed enhancer knockouts in mice, which validated newly identified enhancer-promoter chromatin interactions. "

biorxiv.org/content/10.1101/20

#preprint #generegulation #enhancer #molecularbiology

Last updated 2 years ago

Gene Regulation · @generegulation
514 followers · 65 posts · Server genomic.social

RT @Remeseiro_Lab@twitter.com

1/Pre-print 📢! Rewiring of the landscape and in orchestrates gene expression changes underlying neuron-to-glioma synapse communication. Major actors involved: regulatory networks. Read tweetorial⬇️ biorxiv.org/content/10.1101/20

🐦🔗: twitter.com/Remeseiro_Lab/stat

#enhancer #3Dgenome #glioblastoma #smad3 #pitx1

Last updated 2 years ago

cchaseb · @cchaseb
59 followers · 28 posts · Server mas.to

I want to share this recent review of function. It’s very well written with a brief and clear focus on each topic. It’s delightful.

genomebiology.biomedcentral.co

#enhancer

Last updated 2 years ago