@Nature Ensitrelvir treatment of hamsters infected with the virus possessing Nsp5-M49L/E166A was ineffective; however, #nirmatrelvir or #molnupiravir treatment was effective. Therefore, it is important to closely monitor the emergence of #ensitrelvir-resistant #SarsCoV2 variants to guide antiviral treatment selection.
In vitro and in vivo characterization of #SarsCoV2 resistance to #ensitrelvir
https://www.nature.com/articles/s41467-023-40018-1
#nirmatrelvir #molnupiravir #ensitrelvir #SarsCoV2
''#Ensitrelvir #treatment of hamsters infected with the virus possessing Nsp5-M49L/E166A was ineffective; however, #nirmatrelvir or #molnupiravir treatment was effective. Therefore, it is important to closely monitor the emergence of ensitrelvir-resistant SARS-CoV-2 variants to guide antiviral treatment selection.''
#ensitrelvir #Treatment #nirmatrelvir #molnupiravir
In vitro and in vivo characterization of #SARS-CoV-2 #resistance to #ensitrelvir https://www.nature.com/articles/s41467-023-40018-1 #antivirals #research #science #pharmacology
#sars #resistance #ensitrelvir #antivirals #research #Science #pharmacology
#Efficacy #comparison of #3CLpro #inhibitors #ensitrelvir and #nirmatrelvir against #SARS-CoV-2 in vitro and in vivo https://academic.oup.com/jac/advance-article/doi/10.1093/jac/dkad027/7033725?rss=1
#efficacy #comparison #3clpro #inhibitors #ensitrelvir #nirmatrelvir #sars