Personalised #medicine here we come.. .

COPD & raised #Eosinophils

Anti - IL-4 monoclonal antibody reduces risk of exacerbation
#MedMastodon #biologic #academia #Dupilumab
https://www.nejm.org/doi/full/10.1056/NEJMoa2303951

Just started taking Vitex negundo (Nirgundi). Tried only 200 mg (recommended dose is 5 g).

https://journals.lww.com/ijnp/Fulltext/2013/03020/Antieosinophilic_activity_of_various_subfractions.10.aspx

#NaturalProducts #nirgundi #eosinophils

@bobby115 @AskPippa

I'm still trying to wrap my head around mechanism. Is #Lymphocyte inhibition by mast cells? #Eosinophils/ #basophils?

It will be interesting to see this type of study expanded across larger hospital networks and ultimately #ClinicalTrials!

Hello everybody! #introduction

I'm Paneez, @KhouryMD on various platforms. I do #clinicaltrials and #research in #eosinophils.

Also program director in #Allergy #Immunology so #MedEd is important to me. Passionate about supporting #learners and #FacDev and creating lifelong #mentors by passing it forward.

I also really love coffee and roasting #MedGrind

Interests span many areas so expect posts on lots of different things (views all my own, not employers)

LJI's Croft Lab shares the latest on LIGHT:

Their study, "A Deficiency in the Cytokine TNFSF14/LIGHT Limits Inflammation and Remodeling in Murine Eosinophilic Esophagitis" is important for understanding #allergy and suggests targeting LIGHT may work as a life-saving treatment for this type of allergic disease.

https://doi.org/10.4049/jimmunol.2200326

#immunology #ImmuneSystem #CellBiology #MolecularBiology #Cytokines #TCells #Eosinophils

#IDMastodon #Eosinophils participate in the critical Th2 arm of immunological control of helminthic infections through Fc-receptor-mediated IgE approximation to worm tegument followed by degranulation. Most labs & literature define eosinophils as ⬆️ when they are bw 0.4-0.5 bil/L
https://twitter.com/boggildlab/status/1595120831352668160?s=61&t=h0d67BwuX5xxx0SyYV1Gjg 🧵 by @BoggildLab