It’s finally out! A multi-years effort by Regula Furrer and colleagues from the @biozentrum @unibasel and Jörn Walter at Saarland University. in Nature Metabolism. Supported by @snsf_ch and @ERC_Research.

1/12

doi.org/10.1038/s42255-023-008

#epigenetics #transcription #endurancetraining #ScienceMastodon #exercise #muscle #openaccess

Last updated 1 year ago

Manni_P :mastolove: · @Lost_Paradise
151 followers · 4099 posts · Server troet.cafe
Gabriele Pollara · @gpollara
1085 followers · 3836 posts · Server med-mastodon.com
Epigenetics Podcast · @epigenetics_pod
365 followers · 171 posts · Server podcasts.social

In this episode of the Epigenetics Podcast, we talked with Capucine van Rechem from Stanford University about her work on the impact of chromatin modifiers on disease development and progression.

Listen here: activemotif.com/podcasts-capuc

#chromatin #epigenetics #podcast

Last updated 1 year ago

ISOGG · @isogg
337 followers · 168 posts · Server genealysis.social

“A 2021 study out of Japan showed how targeting genes can regrow teeth in animals. Now, the team has turned to a human clinical trial. By targeting the USAG-1 gene, researchers believe that they can help people without a full set of teeth regrow teeth. The team says that humans have a third set of teeth available as buds, ready to grow as needed.” popularmechanics.com/science/h

#dna #isogg #epigenetics #geneadons

Last updated 1 year ago

Epigenetics Podcast · @epigenetics_pod
365 followers · 170 posts · Server podcasts.social

On this we go back to our Episode #54, there we talked to Yael David about her work on the effects of non-enzymatic covalent histone modifications on .

Listen here: activemotif.com/podcasts-yael-

#throwbackthursday #chromatin #womeninstem #epigenetics

Last updated 1 year ago

Stephen Matheson🌵🌲 · @sfmatheson
713 followers · 713 posts · Server fediscience.org

Judith Zaugg from EMBL
embl.org/groups/zaugg/

How do cells integrate extrinsic signals and intrinsic state? A systems approach

Individual uniqueness (of people) -- molecular basis of
Needed: systems epigenetics framework
signaling -- TFs -- regulatory elements -- genes

tools for inference & evaluation of enhancer-mediated gene regulatory networks called GRaNIE and GRaNPA 😃
embopress.org/doi/full/10.1525

example of problem: embopress.org/doi/full/10.1525

1/2

#cssinglecells23 #variation #epigenetics

Last updated 1 year ago

Hari Tulsidas :verified: · @haritulsidas
320 followers · 1604 posts · Server masto.ai

A new study reveals how inflammation affects the genes that encode bitter taste receptors in our taste buds. The researchers found that inflammation makes mice more sensitive to bitter tastes, which may explain why we lose appetite when sick. The study also used a novel sequencing technique to uncover how epigenetic mechanisms regulate taste-cell gene expression and function. neurosciencenews.com/taste-inf

#bittertaste #inflammation #epigenetics

Last updated 1 year ago

Stephen Matheson🌵🌲 · @sfmatheson
709 followers · 697 posts · Server fediscience.org

Rong Fan at Yale
fan-lab.org/

Spatial Multi-Omics Sequencing at Cellular Level via Deterministic Barcoding in Tissue

first slide called "2006--the ice age of single-cell biology," referring to review article by Johanna Joyce

Recent great technical advance: spatial CITE-seq
nature.com/articles/s41587-023

and spatial ATAC-seq



#cssinglecells23 #epigenetics #Transcriptomics

Last updated 1 year ago

Epigenetics Podcast · @epigenetics_pod
365 followers · 170 posts · Server podcasts.social

In the most recent episode of the Epigenetics Podcast, we talked with Luca Giorgetti from the Friedrich Miescher Institute about his work on long-range transcriptional control by 3D chromosome structure.

Listen here: activemotif.com/podcasts#luca-

#podcast #epigenetics #chromatin #scicomm

Last updated 1 year ago

Epigenetics Podcast · @epigenetics_pod
365 followers · 170 posts · Server podcasts.social

In this episode of the Epigenetics Podcast, we talked with Luca Giorgetti from the Friedrich Miescher Institute about his work on long-range transcriptional control by 3D chromosome structure.

Listen here: activemotif.com/podcasts#luca-

#podcast #epigenetics #chromatin #scicomm

Last updated 1 year ago

TrangAston :verified: · @CastlTrAstonDrs
1408 followers · 2993 posts · Server med-mastodon.com

& clinical observations referring to Betacoronavirus lead to the conjecture that 🦠 may have the ability to infect using a different way than the spike protein. In addition to inducing the death of lymphocytes, thus drastically reducing their population & causing a serious allows it to remain hidden for long periods of latency using them as a in

#IDMastodon #epigenetics #SarsCoV2 #Lymphocytes #immunedeficiency #viralreservoir #LongCovid

Last updated 1 year ago

ISOGG · @isogg
331 followers · 159 posts · Server genealysis.social

“Nandakumar and his team, including senior scientist Valerie Tesmer, showed that a shelterin protein called POT1 uses a cavity the researchers call the "POT-hole" to hide the natural end of the chromosome from being recognized as DNA damage by the ATR machinery. The study is published in the journal Science.
"We dedicate this to the roads in Michigan—not all POT-holes are bad," Nandakumar said.”

phys.org/news/2023-08-pot-hole

#isogg #dna #epigenetics #geneadons

Last updated 1 year ago

Manni_P :mastolove: · @Lost_Paradise
140 followers · 3967 posts · Server troet.cafe
jobRxiv · @jobRxiv
999 followers · 3570 posts · Server mas.to
Manni_P :mastolove: · @Lost_Paradise
140 followers · 3967 posts · Server troet.cafe
Manni_P :mastolove: · @Lost_Paradise
140 followers · 3967 posts · Server troet.cafe
Epigenetics Podcast · @epigenetics_pod
363 followers · 166 posts · Server podcasts.social

In this episode we talked with Mary Gehring from MIT about her work on transgenerational inheritance and imprinting in plants.

Listen here: activemotif.com/podcasts#mary-

#epigenetic #podcast #chromatin #epigenetics

Last updated 1 year ago

Manni_P :mastolove: · @Lost_Paradise
141 followers · 3930 posts · Server troet.cafe
Epigenetics Podcast · @epigenetics_pod
362 followers · 165 posts · Server podcasts.social

In this episode we talked with Mary Gehring from MIT about her work on transgenerational inheritance and imprinting in plants.

Listen here: activemotif.com/podcasts#mary-

#epigenetic #podcast #chromatin #epigenetics

Last updated 1 year ago