🇺🇦 Jocelyn Etienne · @jocelyn_etienne
353 followers · 607 posts · Server scicomm.xyz
@mechanobio
Interesting story where #actin and #keratin organisation are seen to alter differently depending on #polarity protein aPKCλ.
#cytoskeleton #epithelia #mechanics @mechanobiology
#mechanics #epithelia #cytoskeleton #polarity #keratin #actin
🇺🇦 Jocelyn Etienne · @jocelyn_etienne
353 followers · 607 posts · Server scicomm.xyz
@mechanobio Towards an understanding of #epithelia 3D mechanical balance: a topic for which work is very much needed.
@mechanobiology
Dagmar Iber · @iber
80 followers · 37 posts · Server mstdn.science
We also apply #SimuCell3D to the study of two morphogenetic problems: the formation and maintenance of #layered #epithelia and the cellular organization in a #pseudostratified epithelium.
🧵(7/9)
#simucell3d #layered #epithelia #pseudostratified
Classenlab · @classenlab
55 followers · 13 posts · Server drosophila.social
Excited to share our latest paper on "Interface Surveillance", a tissue intrinsic defense system against aberrant cells.
elifesciences.org/articles/80809
#drosophila #epithelia #tumor #mutations #cellfate #cellcompetition #SFB850
#drosophila #epithelia #tumor #mutations #cellfate #cellcompetition #sfb850
🇺🇦 Jocelyn Etienne · @jocelyn_etienne
337 followers · 501 posts · Server scicomm.xyz
@mechanobio
Great preprint, where one can see #epithelia torn by pulling on them or by their internal #tension (generated by #myosin activity).
A slow pull (low strain rate) allows the monolayer to sustain much larger strain.
Finally, they show how #keratin intermediate filaments are key for these mechanical properties.
#keratin #myosin #tension #epithelia
The EMBO Journal · @embojournal
164 followers · 21 posts · Server sciencemastodon.com
What controls dynamic #Epithelial-to-#Mesenchymal Transition of #cancer cells?
Peter ten Dijke Lab at LUMC Leiden identify #plasmamembrane #glycosphingolipid composition and expression of their biosynthesis enzymes as key determinants of dynamic #EMT and #malignant transformation in human #epithelia
#epithelial #mesenchymal #cancer #plasmamembrane #glycosphingolipid #EMT #malignant #epithelia