Research retrospective for mastodon! Here is the paper that really started it all for my lab. In it, we introduce our extremely weird, but also very useful, way of doing Hydrogen Deuterium Exchange Mass Spectromerty to study rapid protein conformational dynamics.

Since then, we've applied this technique to study #proteinevolution , support drug development in #Alzheimer's and #cancer and to improve #epitopemapping .

https://pubs.acs.org/doi/abs/10.1021/ac300365u

#massspec #teammassspec #massspectrometry #science