Dan Bose · @danbose
174 followers · 15 posts · Server biologists.social

Fantastic and important paper on function highlighting Alu repeats in and uaRNAs as drivers of –promoter selectivity and linking to non-coding disease risk variants. Lovely work!!nature.com/articles/s41586-023 (apologies if there's a paywall)

#erna #ernas #enhancer

Last updated 1 year ago

Dan Bose · @danbose
173 followers · 13 posts · Server biologists.social

Super work on - contacts; nice role for in maintaining contacts to promoter bursting too! nature.com/articles/s41588-023

#enhancer #promoter #erna

Last updated 1 year ago

Dan Bose · @danbose
173 followers · 13 posts · Server biologists.social

Hallo all - I guess an introduction might be a good idea!

I'm a mid-career (already!?) group leader, trying to unpick how different aspects of the local environment at work together to regulate and .

We especially like non-coding enhancer , how their structures and dynamic movements make them functional; how disease mutations affect activity and how the enhancer environment affects the regulator CBP.

Super-excited to land here!

#enhancers #transcription #geneexpression #rna #erna #chromatin

Last updated 1 year ago

Lewis Hine · @LewisHine
2 followers · 2 posts · Server mastodon.ozioso.online

, sardine works, . Father earns $1#5 to $#25 a week irregularly during the work season for . Said that he made $#5 a day as a boy, cutting. The mother is a packer makes $#10 a week and upward, during the active season. Another boy, not in the photo, works also. In the front row are , , who cuts regularly--made a dollar in before; , with a badly cut finger, earns #25 cents a day; little works at cartoning. The father is dissatisfied with the irregular income, but cannot see the connection between his early boyhood work and his present stagnation. He is putting his little ones through the same process. Location: , .

//www.loc.gov/pictures/item/2018676745/

#hamiltonfamily #eastport #threemonths #20yearsago #georgehamilton #11yearsold #threehours #theday #byron #erna #8yearsold #maine #photography #lewishine #childlabour #childlabor

Last updated 1 year ago

"**Assessing the degradation of environmental DNA and RNA based on genomic origin in a metabarcoding context"**

onlinelibrary.wiley.com/doi/fu

#eDNA #erna #ena #Metabarcoding #decayrates

Last updated 1 year ago

svenno · @svenno
509 followers · 1176 posts · Server obo.sh
Professor Mark Osborn · @MicrobialLife
531 followers · 124 posts · Server aus.social

screening

Informative new perspectives article in Science journal on how screening of has now become a major tool in , including for SARS-CoV-2 ( )

science.org/doi/10.1126/scienc

#wastewater #pathogen #genetic #epidemiology #COVID19 #edna #environmentaldna #erna

Last updated 2 years ago

Masaru Koido · @mkoido
25 followers · 2 posts · Server genomic.social

Our work to predict transcription of , especially for , from DNA sequences is finally out in @natBME@twitter.com.
Our machine learning tool, MENTR, is available at github.com/koido/MENTR. MENTR can link non-coding associations and cell-type-specific expressions!

nature.com/articles/s41551-022

This was my main work in @ChikashiTerao@twitter.com lab in @RIKEN_IMS@twitter.com. Many thanks to excellent collaborators, amazing datasets, and GPU supercomputer .

#ncrna #erna #GWAS #FANTOM5 #abci

Last updated 2 years ago