Farias &co show that stress-induced phase separation of ERES components into Sec bodies precedes ER exit inhibition in mammalian cells. Initial peer review @ReviewCommons #openaccess: https://journals.biologists.com/jcs/article/135/23/jcs260294/285214/Stress-induced-phase-separation-of-ERES-components
#cellbiology #research #openscience #phaseseparation #ERstress
#openaccess #cellbiology #research #openscience #phaseseparation #erstress
Rong, Zhou &co from the Key Laboratory of Marine Drugs at Ocean University of China show that genetic deletion of the heat shock factor hspa8 leads to selective tissue malformations in zebrafish embryonic development:
https://journals.biologists.com/jcs/article/135/21/jcs259734/278644/Genetic-deletion-of-hspa8-leads-to-selective
#cellbiology #research #zebrafish #embryonicdevelopment #ERstress
#cellbiology #research #zebrafish #embryonicdevelopment #erstress
Our recent review on alternative #ERstress inducers and the #UPR in Progress in Lipid Research is still freely accessible:
https://authors.elsevier.com/c/1g507bFMYznQM
Quick introduction: I’m an aspiring #physicianscientist currently applying to #MSTP #mdphd programs. My research interests are in #metabolism #diabetes #lipidmetabolism #transcriptionfactors and #erstress. In addition to basic science, I love using #rstats #bioconductor and high-throughout sequencing, screens, etc. and I’m currently learning #unix. Personal interests include #weightlifting and #fishing.
#fishing #weightlifting #unix #bioconductor #rstats #erstress #transcriptionfactors #lipidmetabolism #diabetes #metabolism #mdphd #MSTP #physicianscientist
General topics of clinical & research interest:
#psychiatry
#child-psychiatry
#ChildMentalHealth
#neurodevelopment
#autism
#ASD
#ADHD
#tics
#TouretteSyndrome
#Genetics
#Epidemiology
#WolframSyndrome
#ERstress
#Sigma1receptors
#SigmaReceptors
#DRD4
#RYRchannels
#RYR1
#RYR2
#RYR3
#COVID
#COVID19
#LongCOVID
#LongCovidisReal
#LongCOVIDtreatment
#LongCOVIDresearch
#fluvoxamineforCOVID19
#drugRepurposing
#drugrepurposing #fluvoxamineforcovid19 #longcovidresearch #longcovidtreatment #LongCovidisReal #LongCovid #COVID19 #COVID #ryr3 #ryr2 #ryr1 #ryrchannels #drd4 #sigmareceptors #sigma1receptors #erstress #wolframsyndrome #epidemiology #genetics #tourettesyndrome #tics #adhd #asd #Autism #neurodevelopment #childmentalhealth #child #psychiatry