Janet Logan (she/her) 🏳️‍⚧️ · @janetlogan
464 followers · 2480 posts · Server mas.to

Looks like I will be going without estradiol for a few days. Delayed due to the process of getting changed over to the home delivery pharmacy covered under my Medicare Advantage plan. It's been a long time since I've had a gap. Should be fun, for certain values of fun. 🤷‍♀️

Hey, the good news is it's zero copay and zero shipping. And because of the overlap, I'll actually be about 60 days ahead on spiro. And I'll slowly build back a cushion on E too.

#meds #estrogen #estradiol #transgender #trans

Last updated 1 year ago

Mx. Rica 🏳️‍⚧️🇵🇷 · @Rtorres81
79 followers · 1038 posts · Server toot.lgbt

Injection of the week is done so is Bottle 3.

#estradiolvalrate #estradiol

Last updated 1 year ago

Evie (SleepyCatten) · @SleepyCatten
2325 followers · 9061 posts · Server cultofshiv.wtf

N.B.,

It's worth hopping on to this that only affects one's voice.

So, while voice will naturally deepen to varying degrees for trans mascs, cannot affect voice at all for trans fems.

Whenever you hear a trans fem person with a more-feminine voice, that's usually all entirely through voice training / therapy, as only a handful of folks can afford ().

#testosterone #estradiol #vocalfeminisationsurgery #vfs

Last updated 1 year ago

𝙽𝚞𝚐𝚐𝚣 :weed: · @Nuggz
114 followers · 1085 posts · Server hachyderm.io
Evie (SleepyCatten) · @SleepyCatten
1816 followers · 3009 posts · Server cultofshiv.wtf

@Flyingfirepig In case it helps further, estradiol levels during pregnancy levels can rise up to 20,000 pg/mL: which is over 73,000 pmol/L!!!

As such, I wouldn't worry if your estradiol levels reach a few thousand pmol/L during feminising HRT.

#estradiol #hrt #trans #transgender #transfem #diyhrt

Last updated 2 years ago

LorenAmelang · @LorenAmelang
24 followers · 123 posts · Server social.vivaldi.net

@Impossible_PhD Thanks for the balanced view! Especially this:

"You remember back in the 1990’s, when there was that big panic over women’s HRT, when we found out they could cause blood clots? and in the 1970’s, when we found that if it was too old it could cause cancer? All of that came from a combination of drugs called Premarin and Medroxyprogesterone.

We don’t use that stuff anymore, because it is horrible."

Sad how many women, and health professionals, are still stuck there!

#estradiol

Last updated 2 years ago

Amelia · @ami
27 followers · 374 posts · Server mastodon.pl

Jak ja się cieszę, że opakowanie estrofemu kosztuje 4,80 PLN

#estrus #estradiol #hrt #mtf

Last updated 2 years ago

Evie (SleepyCatten) · @SleepyCatten
1776 followers · 2464 posts · Server cultofshiv.wtf

@AngryTransLady I'm a lot luckier than most in many ways, so I really shouldn't complain about my own situation 😞 But yeah, NHS England is awful for trans care.

FWIW, a year's supply of estradiol enanthate from a highly-trusted DIY pharmacy costs under $100 USD.

otkph.com/product/estradiol-en

Their vials have been tested, along with others.

transharmreduction.org/hrt-tes

#trans #transfem #diyhrt #hrt #estradiol

Last updated 2 years ago

today ill be moving from pills to injections, and i am super excited!

#estradiol #hrt #transfemme

Last updated 2 years ago

Little Trans Punk · @littletranspunk
290 followers · 272 posts · Server kolektiva.social

This is entirely for survey purposes, but I've heard there's no study done on this so I want to see what trans people, taking feminising hormones, experience. I am just looking for data points and possibly encourage a study if there's a significant amount of people answering, so please boost this.

If you are trans, AMAB, and take feminizing hormones do you experience any of these?

#study #poll #opensource #science #boost #trans #estradiol #estrogen #antiandrogen #progesterone #hrt #enby

Last updated 2 years ago

In the past two months I've had three medication changes.
I've gone from XR for my to / which has made my worse and isn't providing as much benefit as Adderall did (but the Adderall was making me bitchy and, since I didn't take it on weekends, worthless on weekends where I'd just sleep). It also makes me extremely constipated.
I've switched from to just which seemed to improve my mood but made me a bit more emotional.
Then I just switched from oral to once weekly injections.

I feel like crap. My emotions are a garbage fire on a roller coaster, I have trouble falling asleep and staying asleep (I'm not sure if I'm getting to REM when I am asleep), I get so sleepy during the day that it effects my ability to do my job. My stomach hurts and I've gained about 10 pounds.
Also seasonal allergies so my throat hurts from all the drainage.

That's it. I just wanted to rant to Internet strangers.

I'm on vacation next week which I desperately need. We aren't traveling or doing anything special. My birthday and my wife's birthday are both next week.
We don't travel because there is still a pandemic and she's high risk.

#adderall #adhd #strattera #atomoxetine #insomnia #medroxyprogesterone #progesterone #estradiol

Last updated 2 years ago

Clonehenge · @clonehenge
113 followers · 160 posts · Server mas.to

My friends: there’s more than one way to give your daily medication that extra something! Meet or Henge! Posted on Twitter by @SandySteeley twitter.com/sandysteeley/statu

#estrogen #stonehenge #estradiol #oestrogel

Last updated 2 years ago

Icarosity · @nancywisser
165 followers · 1751 posts · Server mastodon.social

I usually don’t post Stonehenges to my personal account but since I have friends for whom this is a special interest I will share this one: or Henge. There’s more than one way to give your daily that extra something!
From @SandySteeley on Twitter. twitter.com/sandysteeley/statu

#stonehenge #oestrogel #estradiol #estrogen

Last updated 2 years ago

Icarosity · @nancywisser
165 followers · 1751 posts · Server mastodon.social

I usually don’t post Stonehenges to my personal account but since I have friends for whom this is a special interest I will share this one: or Henge. There’s more than one way to give your daily that extra something!
From @SandySteeley on Twitter. twitter.com/sandysteeley/statu

#oestrogel #estradiol #estrogen #stonehenge

Last updated 2 years ago

Wren 🏳️‍⚧️ · @wrenn
76 followers · 47 posts · Server mastodon.lol

for those of you who have switched from pills to injections did you experience noticeable changes? i am thinking about switching, i have been on pills for the last 5 months. thanks.

#hrt #estradiol #transwoman #hormones

Last updated 2 years ago

LorenAmelang · @LorenAmelang
2 followers · 11 posts · Server neuromatch.social

@nadel
"Perhaps now would be a reasonable time to raise questions brought up by the personal histories published so far."

I appreciate the invitation! I'm still thinking about this bit of the Gyuri Buzsaki episode:

"What make the hippocampus special is the granule cell. There is no such cell type in the neocortex. Granule cells keep dividing postnatally and the only cell type known whose life depends on circulating hormones (steroids)."

I've found a few interesting links, including:

Estrogen modulates place learning through estrogen receptors in the hippocampus - Lilia Zurkovsky 2006
(Where they implanted the hormones directly into the rat hippocampus...)

Estrogen Receptors, the Hippocampus, and Memory - Linda A. Bean 2014
(Where they used receptor knockout mice and viral vector delivery of different estrogen receptors to modify the sensitivity to estrogen.)

Do you know of anyone studying this in humans? I guess it would be difficult, since as I (barely and maybe wrongly) understand things, our estradiol level above the blood-brain barrier is higher and poorly correlated with the testable levels circulating below there. And hippocampal E2 is mostly created in the hippocampus itself...

Neurosteroids in Adult Hippocampus of Male and Female Rodents: Biosynthesis and Actions of Sex Steroids - Yasushi Hojo 2018
frontiersin.org/articles/10.33

"Penetration of plasma E2 into the hippocampus, however, is not able to account for the level of hippocampal E2 because hippocampal E2 is much higher than that in plasma."

This graphic is fascinating:
frontiersin.org/files/Articles

Would love to hear anyone's thoughts on the influence of estrogen on spatial awareness and memory!

#hippocampus #estrogen #estradiol #neurosteroids #biosynthesis #granulecell

Last updated 2 years ago

Mx. Alba :blobcatenby: :nd: · @MxAlba
687 followers · 3105 posts · Server mastodon.lol

Second puberty is officially on its way! Stuck my first patch on my body yesterday. Interestingly, the leaflet didn't mention use of the patches by people at all, nor did it mention long-term use. From A to Z, it was all about cis women using the patches for a short period to correct a hormonal imbalance. Like, do people even exist for the medical world?

#estradiol #trans #transfeminine

Last updated 2 years ago

Slenderwoman · @Dimduning
154 followers · 883 posts · Server icosahedron.website

New record! Take that, 500-700 pmol/L target range! I will go boldly into uncharted territory with not-normally-seen-even-during-pregnancy levels!

#estradiol

Last updated 2 years ago

Eldenbrig (She/her) · @Eldenbrig
59 followers · 226 posts · Server lgbtqia.space

Has anyone else been having issues with their patches coming off? I am having to tape mine down constantly. This current patch lasted one day before it started coming off

It's starting to stress me the hell out.

#estradiol

Last updated 2 years ago