https://www.sciencedirect.com/science/article/pii/S2590255523000045 “persistence ..of #hypercoagulability ..such as sustained #inflammation and #endotheliopathy, accompanied by abnormal #fibrin generation and impaired #fibrinolysis. #Platelets seem to be central to the sustained hypercoagulable state, displaying #hyperreactivity to stimuli and increased #adhesive capacity. Platelets also contribute to elevated levels of #thromboinflammatory mediators and #procoagulant extracellular vesicles in individuals with ongoing #PACS”
#hypercoagulability #inflammation #endotheliopathy #fibrin #fibrinolysis #platelets #hyperreactivity #adhesive #thromboinflammatory #procoagulant #pacs
@shanaqui
There's another talk - I barely remember it - but IIRC it was interesting. Apparently mast cells can also release extracellular traps.
Presented by Imre Varju, MD, PhD
"Immune-derived extracellular traps in COVID-19 and other infections" Sept 2020
https://youtu.be/avFT3ypEBas
#immunology #COVID19 #neutrophils #MastCells #mitochondria #NETosis #ExtracellularTraps #thrombosis #clotting #fibrin
#myeloperoxidase
#histones
#immunology #covid19 #Neutrophils #mastcells #mitochondria #netosis #extracellulartraps #thrombosis #clotting #fibrin #myeloperoxidase #histones