Somosdisca :vf: · @Somosdisca
53 followers · 382 posts · Server masto.es
jobRxiv · @jobRxiv
868 followers · 2256 posts · Server mas.to
jobRxiv · @jobRxiv
864 followers · 2133 posts · Server mas.to
Phys.org · @physorg_bot
455 followers · 11669 posts · Server social.platypush.tech
Science Magazine :press: · @ScienceMagazine
392 followers · 52 posts · Server press.coop

New @SciImmunology research involving patient and mouse samples unveils 5 protein markers on macrophages suspected to drive in the lungs and liver. scim.ag/2eZ

#fibrosis #press

Last updated 2 years ago

Hao Yin · @HaoYin
228 followers · 283 posts · Server qoto.org

IL-11 as a therapeutic target for lung in

In Marfan🐭🫁, IL11-GFP reporter is active in Fibroblast but not alveolar epithelia

Dr. Stuart A Cook & Wei Wen Lim lab ATVB 2023
ahajournals.org/doi/10.1161/AT

Also don't miss the story on IL-11 as mediator of Mafan from Circ Res 2022

ahajournals.org/doi/10.1161/CI

#Aortopathy #fibrosis #emphysema #EndothelialCell #marfansyndrome #SmoothMuscleCell

Last updated 2 years ago

Phys.org · @physorg_bot
428 followers · 10390 posts · Server social.platypush.tech
AdriftLab · @AdriftLab
44 followers · 9 posts · Server aus.social

✨NEW PAPER✨Imagine you’ve got a piece of plastic stuck in your stomach - stabbing, poking, and prodding constantly. Besides being incredibly uncomfortable, what would that do to your delicate internal tissues?
One of our Honours students (Hayley) has just published her first, first-author paper in the Journal of Hazardous Materials, investigating the effect that has on the formation of scar tissue within the stomach of from . While scar tissue formation is a natural part of the healing process, excessive scarring can impact tissue function and cause disease, known as paper here ➡️ sciencedirect.com/science/arti...
We found plastic ingestion was significantly related to severe, organ-wide scar tissue formation in the stomach, with some birds exhibiting a near-complete loss of tissue structure (photo panel on LEFT: collagen/scar tissue has stained blue). This is the first time plastic-related scar tissue formation has been documented in wild animals, but what we could see was so severe that it also led us to propose a new disease, – fibrosis as a result of plastic.
As >1200 species are already documented to ingest plastic across both aquatic and terrestrial environments (including us!), our findings have major implications.
 @SeabirdSentinel @TheLabAndField

#AdriftLab #plasticingestion #seabirds #lordhoweisland #fibrosis #openaccess #plasticosis #womeninstem #plasticpollution #sublethaleffects #microplastics #nanoplastics #silicosis

Last updated 2 years ago

AdriftLab · @AdriftLab
44 followers · 9 posts · Server aus.social

✨New paper alert✨Imagine you’ve got a piece of plastic stuck in your stomach - stabbing, poking, and prodding constantly. Besides being incredibly uncomfortable, what would that do to your delicate internal tissues?

One of our Honours students (Hayley) has just published her first, first-author paper in the Journal of Hazardous Materials, investigating the effect that has on the formation of scar tissue within the stomach of from . While scar tissue formation is a natural part of the healing process, excessive scarring can impact tissue function and cause disease, known as paper here ➡️ sciencedirect.com/science/arti

We found plastic ingestion was significantly related to severe, organ-wide scar tissue formation in the stomach, with some birds exhibiting a near-complete loss of tissue structure (photo panel on LEFT: collagen/scar tissue has stained blue). This is the first time plastic-related scar tissue formation has been documented in wild animals, but what we could see was so severe that it also led us to propose a new disease, – fibrosis as a result of plastic.

As >1200 species are already documented to ingest plastic across both aquatic and terrestrial environments (including us!), our findings have major implications.

#AdriftLab #plasticingestion #seabirds #lordhoweisland #fibrosis #openaccess #plasticosis #womeninstem #plasticpollution #sublethaleffects #microplastics #nanoplastics #silicosis

Last updated 2 years ago

a new for that has not yet been tested in humans, but has shown promising results in animal studies. The , called AMY109, is an that binds to and blocks a signaling molecule called -8 (IL-8) that is associated with in , and when tested in monkeys, it was found to reduce the size of and .

sciencealert.com/experimental-

#experimental #antibody #therapy #endometriosis #interleukin #inflammation #lesions #fibrosis

Last updated 2 years ago

Marcel Schulz · @marcelschulz
91 followers · 201 posts · Server genomic.social

RT @KonradHoeft
We are so thrilled to see our new study out in @CellReports today (bit.ly/3XJ5MXB)! We investigated --crosstalk in identifying a platelet-instructed SPP1 macrophage subset that controls fibroblast activation. 1/11

#platelet #macrophage #fibrosis

Last updated 2 years ago

Challenger 🩺 · @SourceControl21
231 followers · 645 posts · Server medibubble.org

Eric Leif Sander et al

december 2021

infection triggers profibrotic responses & lung

doi.org/10.1016/j.cell.2021.11

#SARSCoV2 #macrophage #fibrosis

Last updated 2 years ago

Gonzalo · @gcordova
105 followers · 175 posts · Server mastodon.social
Martin Borch Jensen · @martin
50 followers · 14 posts · Server genomic.social

Exciting story from our advisor Scott Friedman's lab out in Science Translational Medicine, with @GordianBio playing a small role 🎉

Sammi identified new stellate cell behavior to help explain progression, genetic pathways and interventions, 🐭&🧑‍🦰 data, paper has it all!

science.org/doi/10.1126/scitra

#nash #liver #compBio #fibrosis #singlecell

Last updated 2 years ago

Gonzalo · @gcordova
99 followers · 127 posts · Server mastodon.social
Austerity is theft 😷 · @FascistCentre
429 followers · 2482 posts · Server todon.eu
Bernice Hillier · @bernicecbc
272 followers · 64 posts · Server newsie.social

This is a powerful feature about a town left with after an operated & closed there. Quote from article: "The prospect of long-term exposure to free-floating asbestos, over the last half-century, still hangs over the town today, Philpott says. Most people want it gone. Many fear they’re still breathing in what killed their parents, their neighbours." cbc.ca/newsinteractives/featur

#Newfoundland #mining #contamination #asbestos #mine #toxic #tailings #cancer #lungdisease #fibrosis

Last updated 2 years ago

Scientific European · @ScientificEuropean
182 followers · 220 posts · Server toot.community

ILB®, Low Molecular Weight Sulfate (LMW-DS) Shows -Fibrotic Effects in Pre-Clinical Trial | are known to affect several vital organs in the body and are a major cause of mortality and morbidity. There has been a little success in treatment of these diseases so far. ILB®, the Low Molecular Weight Dextran Sulfate (LMW-DS) has shown promising results in a pre-clinical trial...

scientificeuropean.co.uk/medic

#fibrosis #dextran #anti #fibrotic #diseases

Last updated 2 years ago

Fawaz Alzaid, PhD · @DrFAlzaid
46 followers · 236 posts · Server mastodon.world

RT @Brunorm84@twitter.com

Spatial molecular and cellular determinants of activation in liver progression in @JHEP_Reports@twitter.com jhep-reports.eu/article/S2589-

🐦🔗: twitter.com/Brunorm84/status/1

#stat3 #fibrosis #nafld

Last updated 2 years ago

Alejandro Adam · @aleadam
12 followers · 33 posts · Server universeodon.com