#Flozination in HFpEF = less likely to need diuretics started + more likely to discontinue diuretics,
from EMPEROR PRESERVED

https://jamanetwork.com/journals/jamacardiology/fullarticle/2805335?guestAccessKey=491b02a7-5643-44bf-98c0-3873ad7d65bd&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jamacardiology&utm_content=olf&utm_term=052423

I gave my nuanced opinion about #sglt2i in an interview for Nature.
https://www.nature.com/articles/d41586-023-00648-3
#flozination #ChronicKidneyDisease
#diabetes

@mike_johansen you don't think the overall incidence rate was declining even before 2020 though?
(I know it's too early for #flozination effects)

whoah

I had missed this paper from Nature Comm from Freedman, Himmelfarb et al from Seattle

https://www.nature.com/articles/s41467-022-35537-2

Could #Flozination actually reduce cyst growth in #PKD?

yes, mice, organoids etc - but this is a potential U-turn in our understanding

@ChristosArgyrop @mike_johansen @Kidney_boy

Discussing #flozination in cats over at the birdie app. Apparently a SGLT2 inhibitor was approved for the management of #diabetes in our #feline friends. Considering that kidney disease (with or without diabetes) and heart failure is common in cats and #dogs, this could be a game changer for veterinarians, animals and their owners alike. Do we need a RCT, or can we just translate evidence from humans?

Nice summary of Empa-Kidney. #Flozination #Flozinate #Flozinator

http://www.nephjc.com/news/empa-kidney

@ChristosArgyrop @Kidney_boy
Without reading the paper, guess what the last panel on the right means 🤔😏

#VisualAbstract #Hyponatremia #Flozination

Introduction: I do many things, but my passion is #flozination & promoting #glp1.