PLOS Biology · @PLOSBiology
4786 followers · 1118 posts · Server fediscience.org
A network of #plasticity mechanisms: subcortical microstructural (#myelination) plasticity & cortical neurochemical (#GABAergic) plasticity interact via #thalamocortical connectivity to support optimized perceptual decisions @CambridgeABL #PLOSBiology https://plos.io/3YHNvdR
#plosbiology #thalamocortical #gabaergic #myelination #plasticity
PLOS Biology · @PLOSBiology
4786 followers · 1117 posts · Server fediscience.org
A network of #plasticity mechanisms: subcortical microstructural (#myelination) plasticity & cortical neurochemical (#GABAergic) plasticity interact via #thalamocortical connectivity to support optimized perceptual decisions @CambridgeABL #PLOSBiology https://plos.io/3YHNvdR
#plosbiology #thalamocortical #gabaergic #myelination #plasticity
PLOS Biology · @PLOSBiology
4785 followers · 1114 posts · Server fediscience.org
A network of #plasticity mechanisms: subcortical microstructural (#myelination) plasticity & cortical neurochemical (#GABAergic) plasticity interact via #thalamocortical connectivity to support optimized perceptual decisions @CambridgeABL #PLOSBiology https://plos.io/3YHNvdR
#plosbiology #thalamocortical #gabaergic #myelination #plasticity
PLOS Biology · @PLOSBiology
4522 followers · 532 posts · Server fediscience.org
Info from #somatosensory nerves can be actively modified at the #DorsalRootGanglion. This study reveals the existence of tonic & dynamic #GABAergic filtering of action potentials traveling through the #DRG; implications for #PainRelief #PLOSBiology https://plos.io/3VSJFNo
#plosbiology #PainRelief #drg #gabaergic #dorsalrootganglion #somatosensory
PLOS Biology · @PLOSBiology
4497 followers · 514 posts · Server fediscience.org
Info from #somatosensory nerves can be actively modified at the #DorsalRootGanglion. This study reveals the existence of tonic & dynamic #GABAergic filtering of action potentials traveling through the #DRG; implications for #PainRelief #PLOSBiology https://plos.io/3VSJFNo
#plosbiology #PainRelief #drg #gabaergic #dorsalrootganglion #somatosensory
PLOS Biology · @PLOSBiology
4497 followers · 505 posts · Server fediscience.org
Info from #somatosensory nerves can be actively modified at the #DorsalRootGanglion. This study reveals the existence of tonic & dynamic #GABAergic filtering of action potentials traveling through the #DRG; implications for #PainRelief #PLOSBiology https://plos.io/3VSJFNo
#plosbiology #PainRelief #drg #gabaergic #dorsalrootganglion #somatosensory
Tim Viney · @VineyTJ
92 followers · 1 posts · Server neuromatch.socialNew #introduction for neuromatch.social 🙂​
My group investigates and defines cell types and neural circuits of the #thalamus, #hippocampus, and #cortex that contribute to spatial #memory processes.
These processes break down in #Alzheimer's disease. To understand the causes/triggers of #neurodegeneration, we study early-stage #Tau #pathology in the human #brain and in mouse models.
I previously defined various types of retinal ganglion cells using ex vivo #patchclamp recordings during my PhD in #Basel, before moving to #Oxford to work on #GABAergic #neurons of the #hippocampus, followed by the #medialseptum. My favourite technique is in vivo #extracellular recordings and #juxtacellular labelling as it enables identification of single #cells based on their firing patterns, #axon terminal distribution, and #neurochemical profile.
As an #experimentalist, my expertise is primarily in vivo #neurophysiology and #neuroanatomy. I am also interested in #consciousness, the origins of #memory, and regulation of #neuronal activity and #behaviour by #neuropeptides.
#introduction #thalamus #hippocampus #cortex #memory #alzheimer #neurodegeneration #tau #pathology #brain #patchclamp #basel #oxford #gabaergic #neurons #medialseptum #extracellular #juxtacellular #cells #axon #neurochemical #experimentalist #neurophysiology #neuroanatomy #consciousness #neuronal #behaviour #neuropeptides