Referenced link: https://medicalxpress.com/news/2023-06-genetic-mutations-blunt-immune-defenses.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-06-genetic-mutations-blunt-immune-defenses.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1671894577211658244#m

RT by @physorg_com: #Geneticmutations blunt immune defenses in leukemia-linked rare #bonemarrow disorder @CellReports https://linkinghub.elsevier.com/retrieve/pii/S221112472300582X https://medicalxpress.com/news/2023-06-genetic-mutations-blunt-immune-defenses.html

Researchers developed a new algorithm that is six times more reliable than previous models at predicting the effects of #geneticmutations on #RNA formation that may cause rare #hereditarydiseases or #cancer: http://go.tum.de/674287

📷D.Gankin

Referenced link: https://medicalxpress.com/news/2023-05-genetic-mutations-contribute-adult-epilepsy.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-05-genetic-mutations-contribute-adult-epilepsy.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1653081360322420737#m

RT by @physorg_com: Study identifies #geneticmutations that contribute to adult epilepsy @MassGenBrigham @jamaneuro https://jamanetwork.com/journals/jamaneurology/fullarticle/2804531 https://medicalxpress.com/news/2023-05-genetic-mutations-contribute-adult-epilepsy.html

Referenced link: https://medicalxpress.com/news/2023-04-method-accuracy-dna-sequencing-fold.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-04-method-accuracy-dna-sequencing-fold.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1651944622783107072#m

RT by @physorg_com: New method improves accuracy of #DNA sequencing 1,000-fold to detect rare #geneticmutations @broadinstitute @NatureGenet https://www.nature.com/articles/s41588-023-01376-0 https://medicalxpress.com/news/2023-04-method-accuracy-dna-sequencing-fold.html

Good news! Constructive guidance on how to prevent an ecological catastrophe - but only if enough humans follow the scientific guidance (which they have not been doing historically)

A parable "You can lead a horse to water - but you can't make it drink".

The 'key' posts that are pinned on my home profile & my blog generally use the science of psychology & ecology, and my personal experience in regard to discussing environmental topics with adults - to detail the behavioral psychological, sociopolitical, and socioeconomic issues that are preventing humans from mitigating their ecologically degrading activities.

The epistemology to success is included in the following 'key' articles. Conversely, success means that failures must be addressed (rather than ignoring them due to cognitive dissonance).

If the 'key' general plans are not followed by a sufficient quantity of key decision-makers - climate heating will decimate our societies (it's only a matter of when not if)

1. Wannabe dictators need only apply (mentions evil agents) https://qoto.org/@empiricism/109436037494876506

2. The concerning behavioral psychology of ecocide & how to stop it. https://qoto.org/@empiricism/109467480926903109

3. psychology 101 - explained in layperson's terms. https://qoto.org/@empiricism/109451868659033738

4. (May cause denial) Health damaging behaviors. Not safe for children. https://qoto.org/@empiricism/109446137039667007

5. The unpleasant psychology of the Darkside. (Age advisory rating 15+ or with adult supervision) https://empiricalperspective.home.blog/2022/12/04/the-unpleasent-psychology-of-the-darkside-age-advisory-rating-15-or-with-adult-supervision/

6. Democracy for grownups (Justice!).https://empiricalperspective.home.blog/2022/10/17/democracy-for-grownups-i-e-civilized-people/

7. The nepotism of plutocracy. https://empiricalperspective.home.blog/2022/09/30/the-nepotism-of-plutocracy/

#ClimateChange #ClimateBomb #ClimateAction #climatejustice #science #nature #ClimateProtests #sucess #CircularEconomy #tech #food #ecology #EcologicalRestoration #flora #fauna #RenewableEnergy #wildlife #habitats #health #biosphere #forests #rivers #oceans #ecology #sustainabilty #CitizensAssembly #CircularEconomy

#ClimateHeating #heatwaves #droughts #famine #inhabitable #SpeciesExtinction #corporate #ecocide #politics #business #FossilFuels #WoodFuels #mining #pollution #corporations #money #greed #apathy #coruption #Greenwash #deception #AirPollution #dementia #cancer #diseases #RespiratoryDiseases #heartAttacks #strokes #plastic #pollution

#EvolutionaryBiology #Neuroscience #CogntivePsychology #SocialPsychology #DevelopmentalPsychology #Cognitive #dissonance #psychological #VirtueSignaling #heuristics #CognitiveDissonance

#organisms #plants #animals, #fungi #bacteria #mammals #HomoSapiens #evolution #NaturalSelection #SexualSelection #GeneticMutations #biology #biotic #NervousSystem

#SocialMedia #Twitter, #Facebook, #YouTube #Mastodon #abiotic #technologies

#psychology 101 - explained in layperson's terms.

A multitude of interdisciplinary scientific publications can be referenced for the following information. Basically, I will not be "cherry-picking" research as the following info represents the general scientific literature on the key subjects. For example #EvolutionaryBiology #Neuroscience #CogntivePsychology #SocialPsychology #DevelopmentalPsychology

Therefore, whilst I may not have the title of, for example, professor, that isn't relevant in the context of the following information.

The scientific literature is the authority, not the individual. Of course, most often than not, those with a degree, master's, doctorate, professor, etc - will be more informed of the scientific literature.

I welcome critical evaluation of the following information. FYI, I will intentionally be using "everyday" language. Although, I will # the key scientific terminology.

Genetic replication is the "meaning" of life. Though genes have zero agency - that's why I put quotation marks around "meaning". Agency (meaning, motivation, etc) is an evolutionary adaptation. Some organisms have agency, for example, humans, whilst others don't. For example, plants and fungi.

And of course, if you're sitting on a chair whilst you read this (or deny the information) - the chair has no intrinsic meaning. The universe has no intrinsic meaning. Assuming our "universe" is not one dimension amongst a multitude of multiverses that we can't perceive. I don't think so, but that's only speculation.

1. All living #organisms (plants, animals, fungi, bacteria, etc) including #HomoSapiens are the outcome of #evolution - #NaturalSelection that includes #SexualSelection are the regulatory filters of #geneticMutations

All mammals share a common ancestor. Humans have hands with opposable digits because we are primates (all primates share common anatomical and physiological features. & to some degree - behavioral psychologies)

Sentient organisms such as #mammals have psychological behavioral - #adaptations, #byproducts & #maladaptations (& some #GeneticDrift).

However, the majority of organisms on planet earth, including some humans, do not know they are animals. Even though they behave exactly as animals do #poop #breath #eat #drink #etc

Consciousness is an adaptation #InformationProcessing.

The majority of human physiological functioning is implicit (non-conscious biological processors). The biological sciences have provided explicit knowledge regarding how our implicit physiological systems function. For example, external sound #objective is converted into #Electrochemical signals #subjective and these signals tend to be transmitted #NervousSystem toward the part of the brain termed the #AuditoryCortex

Thoughts and feelings #emotions may be implicit #MetaCognition or explicit #cognition.

The background knowledge of evolutionary biology (plus the subjects that have been #) can be used to improve any individual's self-awareness - therefore increasing their self-understanding of their Cognitive #heuristics.

Metacognitive is an adaptive system. Therefore it can be updated when a person recognizes how and why their mind functions.

Evolutionary biology is the study of how? and why? organisms evolved and what they do with those adaptations. And how they may continue to evolve. To reiterate, evolution is the outcome of natural selection (genetic replication). Therefore, evolution is not aiming for the "perfection" of an organism.

Organisms may have maladaptations because the environmental conditions (variables) can change faster than evolutionary processors. The behaviors that explicitly exemplify this are the human maladaptations that are degrading their environments (oh dear!). However, many of those behaviors are due to nurturing. For example, children are taught to eat meat and blame vegans for choosing a more ethical diet. Nurturing, for example, learning and associated learning are also evolutionary adaptations (heuristics)

Questions and or constructive critique of this toot, are most welcome. However, what would be even more welcome would be to paraphrase "Show me the evidence!"

In the context of evolutionary biology - there are research papers going back hundreds of years ( i.e., Scientific publications going back as far as Charles Darwin et al.)

Although, for any newbies to the subject - I recommend the 'Thirteen Misunderstandings
About Natural Selection "

Al-Shawaf, L., Zreik, K., & Buss, D. M. (2018b). Thirteen Misunderstandings About Natural Selection. Encyclopedia of Evolutionary Psychological Science, 1–14. https://doi.org/10.1007/978-3-319-16999-6_2158-1

Open access copy https://www.researchgate.net/publication/325999471_13_Misunderstandings_about_Natural_Selection

Curiosity is only natural! Evolution is only natural. Repressing knowledge is also natural. But is it healthy?

#psychology 101 - explained in layperson's terms.

A multitude of interdisciplinary scientific publications can be referenced for the following information. Basically, I will not be "cherry-picking" research as the following info represents the general scientific literature on the key subjects. For example #EvolutionaryBiology #Neuroscience #CogntivePsychology #SocialPsychology #DevelopementalPsychology

Therefore, whilst I may not have the title of, for example, professor, that isn't relevant in the context of the following information.

The scientific literature is the authority, not the individual. Of course, most often than not, those with a degree, master's, doctorate, professor, etc - will be more informed of the scientific literature.

I welcome critical evaluation of the following information. FYI, I will intentionally be using "everyday" language. Although, I will # the key scientific terminology.

Genetic replication is the "meaning" of life. Though genes have zero agency - that's why I put quotation marks around "meaning". Agency (meaning, motivation, etc) is an evolutionary adaptation. Some organisms have agency, for example, humans, whilst others don't. For example, plants and fungi.

And of course, if you're sitting on a chair whilst you read this (or deny the information) - the chair has no intrinsic meaning. The universe has no intrinsic meaning. Assuming our "universe" is not one dimension amongst a multitude of multiverses that we can't perceive. I don't think so, but that's only speculation.

1. All living #organisms (plants, animals, fungi, bacteria, etc) including #HomoSapiens are the outcome of #evolution - #NaturalSelection that includes #SexualSelection are the regulatory filters of #geneticMutations

All mammals share a common ancestor. Humans have hands with opposable digits because we are primates (all primates share common anatomical and physiological features. & to some degree - behavioral psychologies)

Sentient organisms such as #mammals have psychological behavioral - #adaptations, #byproducts & #maladaptations (& some #GeneticDrift).

However, the majority of organisms on planet earth, including some humans, do not know they are animals. Even though they behave exactly as animals do #poop #breath #eat #drink #etc

Consciousness is an adaptation #InformationProcessing.

The majority of human physiological functioning is implicit (non-conscious biological processors). The biological sciences have provided explicit knowledge regarding how our implicit physiological systems function. For example, external sound #objective is converted into #Electrochemical signals #subjective and these signals tend to be transmitted #NervousSystem toward the part of the brain termed the #AuditoryCortex

Thoughts and feelings #emotions may be implicit #MetaCognition or explicit #cognition.

The background knowledge of evolutionary biology (plus the subjects that have been #) can be used to improve any individual's self-awareness - therefore increasing their self-understanding of their Cognitive #heuristics.

Metacognitive is an adaptive system. Therefore it can be updated when a person recognizes how and why their mind functions.

Evolutionary biology is the study of how? and why? organisms evolved and what they do with those adaptations. And how they may continue to evolve. To reiterate, evolution is the outcome of natural selection (genetic replication). Therefore, evolution is not aiming for the "perfection" of an organism.

Organisms may have maladaptations because the environmental conditions (variables) can change faster than evolutionary processors. The behaviors that explicitly exemplify this are the human maladaptations that are degrading their environments (oh dear!). However, many of those behaviors are due to nurturing. For example, children are taught to eat meat and blame vegans for choosing a more ethical diet. Nurturing, for example, learning and associated learning are also evolutionary adaptations (heuristics)

Questions and or constructive critique of this toot, are most welcome. However, what would be even more welcome would be to paraphrase "Show me the evidence!"

In the context of evolutionary biology - there are research papers going back hundreds of years ( i.e., Scientific publications going back as far as Charles Darwin et al.)

Although, for any newbies to the subject - I recommend the 'Thirteen Misunderstandings
About Natural Selection "

Al-Shawaf, L., Zreik, K., & Buss, D. M. (2018b). Thirteen Misunderstandings About Natural Selection. Encyclopedia of Evolutionary Psychological Science, 1–14. https://doi.org/10.1007/978-3-319-16999-6_2158-1

Open access copy https://www.researchgate.net/publication/325999471_13_Misunderstandings_about_Natural_Selection

Curiosity is only natural! Evolution is only natural. Repressing knowledge is also natural. But is it healthy?

#psychology 101 - explained in layperson's terms.

A multitude of interdisciplinary scientific publications can be referenced for the following information. Basically, I will not be "cherry-picking" research as the following info represents the general scientific literature on the key subjects. For example #EvolutionaryBiology #Neuroscience #CogntivePsychology #SocialPsychology #DevelopementalPsychology

Therefore, whilst I may not have the title of, for example, professor, that isn't relevant in the context of the following information.

The scientific literature is the authority, not the individual. Of course, most often than not, those with a degree, master's, doctorate, professor, etc - will be more informed of the scientific literature.

I welcome critical evaluation of the following information. FYI, I will intentionally be using "everyday" language. Although, I will # the key scientific terminology.

Genetic replication is the "meaning" of life. Though genes have zero agency - that's why I put quotation marks around "meaning". Agency (meaning, motivation, etc) is an evolutionary adaptation. Some organisms have agency, for example, humans, whilst others don't. For example, plants and fungi.

And of course, if you're sitting on a chair whilst you read this (or deny the information) - the chair has no intrinsic meaning. The universe has no intrinsic meaning. Assuming our "universe" is not one dimension amongst a multitude of multiverses that we can't perceive. I don't think so, but that's only speculation.

1. All living #organisms (plants, animals, fungi, bacteria, etc) including #HomoSapiens are the outcome of #evolution - #NaturalSelection that includes #SexualSelection are the regulatory filters of #geneticMutations

All mammals share a common ancestor. Humans have hands with opposable digits because we are primates (all primates share common anatomical and physiological features. & to some degree - behavioral psychologies)

Sentient organisms such as #mammals have psychological behavioral - #adaptations, #byproducts & #maladaptations (& some #GeneticDrift).

However, the majority of organisms on planet earth, including some humans, do not know they are animals. Even though they behave exactly as animals do #poop #breath #eat #drink #etc

Consciousness is an adaptation #InformationProcessing.

The majority of human physiological functioning is implicit (non-conscious biological processors). The biological sciences have provided explicit knowledge regarding how our implicit physiological systems function. For example, external sound #objective is converted into #Electrochemical signals #subjective and these signals tend to be transmitted #NervousSystem toward the part of the brain termed the #AuditoryCortex

Thoughts and feelings #emotions may be implicit #MetaCognition or explicit #cognition.

The background knowledge of evolutionary biology (plus the subjects that have been #) can be used to improve any individual's self-awareness - therefore increasing their self-understanding of their Cognitive #heuristics.

Metacognitive is an adaptive system. Therefore it can be updated when a person recognizes how and why their mind functions.

Evolutionary biology is the study of how? and why? organisms evolved and what they do with those adaptations. And how they may continue to evolve. To reiterate, evolution is the outcome of natural selection (genetic replication). Therefore, evolution is not aiming for the "perfection" of an organism.

Organisms may have maladaptations because the environmental conditions (variables) can change faster than evolutionary processors. The behaviors that explicitly exemplify this are the human maladaptations that are degrading their environments (oh dear!). However, many of those behaviors are due to nurturing. For example, children are taught to eat meat and blame vegans for choosing a more ethical diet. Nurturing, for example, learning and associated learning are also evolutionary adaptations (heuristics)

Questions and or constructive critique of this toot, are most welcome. However, what would be even more welcome would be to paraphrase "Show me the evidence!"

In the context of evolutionary biology - there are research papers going back hundreds of years ( i.e., Scientific publications going back as far as Charles Darwin et al.)

Although, for any newbies to the subject - I recommended the 'Thirteen Misunderstandings
About Natural Selection "

Al-Shawaf, L., Zreik, K., & Buss, D. M. (2018b). Thirteen Misunderstandings About Natural Selection. Encyclopedia of Evolutionary Psychological Science, 1–14. https://doi.org/10.1007/978-3-319-16999-6_2158-1

Open access copy https://www.researchgate.net/publication/325999471_13_Misunderstandings_about_Natural_Selection

Curiosity is only natural! Evolution is only natural. Repressing knowledge is also natural. But is it healthy?

MIT researchers have developed a novel tool, called PASTE, that can insert large gene sequences where they want in the genome. This approach can be used to treat cystic fibrosis & Leber congenital amaurosis.

https://www.nature.com/articles/s41587-022-01527-4

#genetherapy #geneediting #geneticmutations #geneticcorrection #crispr

Referenced link: https://phys.org/news/2022-08-asexual-reproduction-genetic-mutations.html
Discuss on https://discu.eu/q/https://phys.org/news/2022-08-asexual-reproduction-genetic-mutations.html

Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/physorg_com/status/1554200813345570816#m

#Asexualreproduction leads to harmful #geneticmutations https://onlinelibrary.wiley.com/doi/10.1111/evo.14509 https://phys.org/news/2022-08-asexual-reproduction-genetic-mutations.html

Referenced link: https://medicalxpress.com/news/2022-07-tumors-specific-genetic-mutations-response.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2022-07-tumors-specific-genetic-mutations-response.html

Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/medical_xpress/status/1547201191452590081#m

RT by @physorg_com: Tumors with specific #geneticmutations show response to #immunecheckpointblockade therapy @NatureGenet https://www.nature.com/articles/s41588-022-01108-w https://medicalxpress.com/news/2022-07-tumors-specific-genetic-mutations-response.html

Referenced link: https://phys.org/news/2022-05-insights-link-genetic-mutations-biological.html
Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/physorg_com/status/1526575501002907649#m

New insights on link between #geneticmutations and #biologicalevolution @UTM @sciencemagazine https://doi.org/gp53gw https://phys.org/news/2022-05-insights-link-genetic-mutations-biological.html