Interesting and important paper solving structures of the RecA filament bound to the various proteins it activates, including LexA.

https://www.pnas.org/doi/10.1073/pnas.2217493120

Loop 2 of RecA intimately associates with bound LexA. Very strongly complementing our findings that phosphorylation of L2 regulates LexA cleavage in the mycobacterial DDR:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389330/

#recA #mutagenesis #dnadamage #genomicintegrity