Interesting paper from Tatjana Trcek lab.
She & her team looked at fly #GermGranules nucleation and, well... the title says it all:

"Proteins rather than mRNAs regulate nucleation and persistence of Oskar germ granules in Drosophila "

#mRNA #mRNALocalization #Drosophila #LLPS

It is also her 1st paper as #NewPI so congrats are in order.

https://www.sciencedirect.com/science/article/pii/S2211124723007349

A very nice review on RNA granules from Geraldine Seydoux's lab at Genes & Development.

"RNA granules: functional compartments or incidental condensates?"

#RNA #granules #mRNA #phaseseparation #translation #splicing #Pbodies #StressGranules
#GermGranules

https://genesdev.cshlp.org/content/37/9-10/354.abstract

RNA/protein condensates called "germ granules" are ubiquitous among animal #GermCells. @gavislab shows that #Drosophila #GermGranules initially protect RNAs but then become sites of selective mRNA degradation, supporting germ cell development #PLOSBiology https://plos.io/3UxHmR7

RNA/protein condensates called "germ granules" are ubiquitous among animal #GermCells. @gavislab shows that #Drosophila #GermGranules initially protect RNAs but then become sites of selective mRNA degradation, supporting germ cell development #PLOSBiology https://plos.io/3UxHmR7

RNA/protein condensates called "germ granules" are ubiquitous among animal #GermCells. @gavislab shows that #Drosophila #GermGranules initially protect RNAs but then become sites of selective mRNA degradation, supporting germ cell development #PLOSBiology https://plos.io/3UxHmR7