“Even though they constitute a small fraction of the total number of cells later on, the founder cells that stay in the germinal center for a long time are still doing their job,"
"But just how well those founder B cells do their jobs, and whether naïve recruits cramp their style and reduce their efficacy, remains to be seen." #germinalcenters #bcells #respiratoryviruses
#germinalcenters #Bcells #RespiratoryViruses
"Immunoglobulin VDJ repertoires reveal hallmarks of germinal centers in unique cell clusters isolated from zebrafish (Danio rerio) lymphoid tissues. " #germinalcenters #Bcells #antibodies #affinitymaturation #somatichypermutation
https://www.frontiersin.org/articles/10.3389/fimmu.2022.1058877/full?utm_source=F-AAE&utm_medium=EMLF&utm_campaign=MRK_1992460_a0P58000000G0YLEA0_Immuno_20221215_arts_A&id_mc=311800697&utm_source=sfmc&utm_medium=email&utm_campaign=Article+Alerts+V4.1-Frontiers&utm_id=1992460
#antibodies #germinalcenters #Bcells #affinitymaturation #somatichypermutation