Mike Honey · @mike_honey_
2526 followers · 1880 posts · Server aus.social
Here's the latest variant picture for Spain.
A resurgence from XBB.1.5.* "Kraken" (26%) appears to have supressed the new EG.5.* "Eris" variant (19%).
Among the individual XBB.1.5.* "Kraken" sub-lineages, the new "FLip" lineage GK.2 lineage (12%) appears to be driving the recent growth.
GK is an alias for XBB.1.5.70.1. XBB.1.5.70 added the adjacent Spike L455F and F456L mutations, hence the "FLip" tag. GK.2 adds the Spike V511I mutation.
Yunlong Cao explained the advantage of this pair of mutations here:
https://twitter.com/yunlong_cao/status/1687879512237993986?s=20
The sample volumes look representative up to August 1.
#COVID19 #Spain #GK_2 #FLip #EG_5 #Eris
Interactive genomic sequencing dataviz, code, acknowledgements and more info here:
https://github.com/Mike-Honey/covid-19-genomes#readme
#COVID19 #spain #gk_2 #flip #eg_5 #eris
Mike Honey · @mike_honey_
2521 followers · 1874 posts · Server aus.social
Here's the latest variant picture for the new "FLip" variant GK.2.
The leading countries reporting GK.2 are Spain (11%) and Italy (7%).
GK.2 is from the XBB.1.5.* "Kraken" clan; GK is an alias for XBB.1.5.70.1. XBB.1.5.70 added the adjacent Spike L455F and F456L mutations, hence the "FLip" nickname. GK.2 adds the Spike V511I mutation.
Yunlong Cao explained the advantage of this pair of mutations here:
https://twitter.com/yunlong_cao/status/1687879512237993986?s=20
HT Raj Rajnarayanan (https://twitter.com/RajlabN) for the clever "FLip" nickname.
Sample volumes from many countries are now very thin and patchy, leading to some variations.
#COVID19 #flip #gk_2 #xbb_1_5 #kraken