Gizmodo: An Existing Drug for Multiple Sclerosis Might Be Useful for Alzheimer's Too, Study Finds https://gizmodo.com/ms-ponesimod-might-be-useful-alzheimers-therapy-study-1850803952?utm_source=regular #insulindegradingenzyme #healthmedicalpharma #neuroinflammation #alzheimersdisease #amyloidplaques #amyloidosis #amyloidbeta #macrophages #glialcells #microglia #zhihuizhu #trem2

Is the future of computing biological? - Enlarge (credit: Andriy Onufriyenko)

Trying to make computers ... - https://arstechnica.com/?p=1920548 #artificialintelligence #computerscience #humanbraincells #biocomputers #glialcells #computer #science

Ars Technica: Is the future of computing biological? https://arstechnica.com/?p=1920548 #Tech #arstechnica #IT #Technology #ArtificialIntelligence #Computerscience #humanbraincells #biocomputers #glialcells #computer #Science

Who works side by side with #neurons #glialcells
https://www.youtube.com/watch?v=AQvlP3isn68

Check this video of #neurons and #glialcells, our passion :underheart:
https://youtu.be/VQP_vMxI4SI

#BrainTumors 🧠

🔸 One source of brain tumors is metastasis -- which are spreads from other tumors, so for instance, lung tumors.

🔸 The brain tumors are a problem because they exist within the cranium, and the cranium is a fixed, bony container. It can't expand. And as a tumor expands, the cranium is not going to expand. It's going to increase the pressure and we're going to have a problem.

🔸 Neurons don't make tumors because they don't divide at all, and they don't get into this uncontrolled division. So what makes tumors? Well, it's other cell types within the brain. And the primary one that does this are #GlialCells.

🔸 Glial cells don't have the limits on division that neurons do. So, glial cells can divide and make these tumors. And so, #gliomas, tumors of glial cells, are the most common type of brain tumor.

🔸 Another type of brain tumor is the type that comes from a division of meningeal cells, and these are called #meningiomas.

🔸 And finally, the other major type of brain tumor is are tumors that come from glandular cells.

🔸 These glandular cells are not neurons. They're gland cells, and they can divide without control. The other gland that we have in our head is called the pituitary, and these pituitary cells can also divide and that's called 'pituitary adenomas'. These #PituitaryAdenoma's are fairly common. They account for about 10 to 25% of inter-cranial tumors.

🖼️ Image source: https://images.app.goo.gl/hfXZKhrd7ahacDsx9

🔴 Demyelinating Diseases

🔸 The #glialcells that make the myelin are of different types that make it (myelin) in the central nervous system and in the peripheral nervous system. And because of that, people who get a demyelinating disease, get it either in the central nervous system or in the peripheral nervous system -- but not in both.

🔸 So the problem is either in the #oligodendrocytes (and the interaction between the oligodendrocytes and the axon) -- in which case you get a central demyelinating disease, and the most common by far is multiple #sclerosis -- or there's a problem in the #SchwannCell and its connection to the axon, and in that case you can get a variety.

🔸 There are a diverse group of hereditary neuropathies called Charcot-Marie Tooth, which are #DemyelinatingDiseases. They're inherited and they typically progress and become worse with time.
🔸 There's also an acute demyelinating disease called Guillain–Barré, which typically has a very quick onset, it's inflammatory, and luckily it goes away after a while.