Papers in press time @jbiolchem! Periscope protein adhesin domain structures-an incredible effort by all my excellent colleagues. Structures reveal lectin homology domains, but...here's the kicker - no evidence of #glycan binding. 🤔 #Proteins #crystallography

https://www.jbc.org/article/S0021-9258(23)00068-6/fulltext

RT @LauraPolito8@twitter.com

📢👇Have a look to our last paper! A new protocol to produce #glycan functionalized #goldnanoparticles by #microfluidics approach. Great collaborations! Photo‐Induced Microfluidic Production of Ultrasmall Glyco Gold Nanoparticles https://onlinelibrary.wiley.com/doi/10.1002/anie.202210140#.Y4iL3dZKc50.twitter

🐦🔗: https://twitter.com/LauraPolito8/status/1598274988158889985

An #introduction into our work on #glycotime! We are a lab joint between the Francis Crick Institute and the Department of Chemistry at Imperial College London. We develop what we call chemical "precision tools" to investigate protein #glycosylation. These tools are specific for individual #glycosyltransferases, #glycan subtypes or cell lines. We employ methods of #chembio including #OrgChem, protein engineering, #glycoproteomics, #imaging, #chemoenzymatic synthesis and drug discovery.