Papers in press time @jbiolchem! Periscope protein adhesin domain structures-an incredible effort by all my excellent colleagues. Structures reveal lectin homology domains, but...here's the kicker - no evidence of #glycan binding. 🤔 #Proteins #crystallography
#glycan #proteins #crystallography
RT @LauraPolito8@twitter.com
📢👇Have a look to our last paper! A new protocol to produce #glycan functionalized #goldnanoparticles by #microfluidics approach. Great collaborations! Photo‐Induced Microfluidic Production of Ultrasmall Glyco Gold Nanoparticles https://onlinelibrary.wiley.com/doi/10.1002/anie.202210140#.Y4iL3dZKc50.twitter
🐦🔗: https://twitter.com/LauraPolito8/status/1598274988158889985
#glycan #goldnanoparticles #microfluidics
An #introduction into our work on #glycotime! We are a lab joint between the Francis Crick Institute and the Department of Chemistry at Imperial College London. We develop what we call chemical "precision tools" to investigate protein #glycosylation. These tools are specific for individual #glycosyltransferases, #glycan subtypes or cell lines. We employ methods of #chembio including #OrgChem, protein engineering, #glycoproteomics, #imaging, #chemoenzymatic synthesis and drug discovery.
#introduction #Glycotime #glycosylation #glycosyltransferases #glycan #chembio #OrgChem #glycoproteomics #imaging #chemoenzymatic