CellBioNews · @cellbionews
103 followers · 1798 posts · Server scientificnetwork.de#Glucagon #receptor structures uncover new #arrestin interaction mechanism.
#signalling #transduction #GPCR
https://phys.org/news/2023-08-glucagon-receptor-uncover-arrestin-interaction.html
#glucagon #receptor #arrestin #signalling #transduction #gpcr
Gaspar Jekely · @jekely
366 followers · 1 posts · Server biologists.social
Our favourite #Platynereis #opsin now in the mammalian brain as a new #optogenetic tool!
"Here we ... found that the Platynereis dumerilii ciliary opsin ... is an efficient, versatile, light-activated bistable GPCR that can suppress synaptic transmission in mammalian neurons with high temporal precision in-vivo "
#platynereis #opsin #optogenetic #neuroscience #gpcr
Martin Vögele · @martinvoegele
407 followers · 126 posts · Server fediscience.org#ScienceJob opening for #GPCR #DrugDiscovery experts.
https://boards.greenhouse.io/schrdinger/jobs/5530548003
#drugdiscovery #gpcr #sciencejob
CellBioNews · @cellbionews
49 followers · 1128 posts · Server scientificnetwork.deNovel living #yeast-based dual #biosensor for detecting #peptide variants.
#biotechnology #signalling #GPCR
https://phys.org/news/2023-04-yeast-based-dual-biosensor-peptide-variants.html
#yeast #biosensor #peptide #biotechnology #signalling #gpcr
Corrosive Dream · @corrosivedream
297 followers · 1250 posts · Server troet.cafeIn dieser Fallserie zur Behandlung von #LongCovid durch #Immunadsorption konnte leider keine Wirksamkeit festgestellt werden.
Mögliche Ursachen sind
- Membrangebundene #Autoantikörper konnten nicht entfernt werden.
- Die Krankheit war bereits chronifiziert.
- Autoantikörper sind nur ein Epiphänomen.
- Autoantikörper werden zu schnell nachgebildet.
#gpcr #mecfs #PostCovid #Apherese #autoantikorper #Immunadsorption #LongCovid
Dziga Vertov 2 · @DzigaVertov2
120 followers · 1734 posts · Server mas.to
Looking forward to reading Saturday's book of the day:
#GPCR #China #maozedong
CellBioNews · @cellbionews
36 followers · 809 posts · Server scientificnetwork.de#Receptor 'blasting' #visualized: Scientists develop new technology to study important receptors.
https://phys.org/news/2023-03-receptor-blasting-visualized-scientists-technology.html
#receptor #visualized #gpcr #sensing #signalling
Fenjan🦖 · @fenjan
11 followers · 249 posts · Server sigmoid.socialdate: 2023-02-10 10:52:06
by: Peter Kenny 🇹🇹🇬🇧🇧🇷🇺🇦🌻🇪🇺🇲🇦
#PhD opportunity - Analysis/prediction of ligand signaling pathways in G protein-coupled receptors at (University of Glasgow/Queens University Belfast UK) #GPCR #GPR48 #pharmacol #simulations #ML https://www.gla.ac.uk/colleges/mvls/graduateschool/northwestbio/projects/bioscience/integratedapproachesinpharmacologycomputersimulationsandmachinelearning/
🐦🔗: https://twitter.com/twitter/statuses/1623998237425139712
#PhdPosition
#phd #gpcr #gpr48 #pharmacol #simulations #ml #phdPosition
Dziga Vertov 2 · @DzigaVertov2
79 followers · 907 posts · Server mas.to
Sunday's book of the day is:
#GPCR #China #maoism #Mao #culturalrevolution
#culturalrevolution #mao #maoism #China #gpcr
Dziga Vertov 2 · @DzigaVertov2
56 followers · 448 posts · Server mas.to
Saturday's book of the day is:
#GPCR #Chineserevolution #China #revolution #art
#art #revolution #China #chineserevolution #gpcr
Alex Kwan · @alexkwan
577 followers · 15 posts · Server neuromatch.social
Made our own #GPCR #gingerbread cookies. Few with some serious mutations 😂. h/t @cllantz for the fun cookie cutters
Patrick van der Wel · @p_vanderwel
97 followers · 97 posts · Server mastodon.social"Slow conformational dynamics of the human A2A adenosine receptor are temporally ordered. " https://www.sciencedirect.com/science/article/pii/S0969212621004172 … #GPCR #dynamics by Rajan Lamichhane, Matthew Eddy and co-authors
Martin Vögele · @martinvoegele
312 followers · 70 posts · Server fediscience.orgNew #preprint about PENSA, our flexible #OpenSource software package for comprehensive and thorough investigation of biomolecular conformational ensembles:
https://arxiv.org/abs/2212.02714
In three real-world examples, we show how it can be used to understand an #enzyme mechanism, #DNA #forcefield parameters, and #signaling in an #opioid #receptor.
Please share widely with the #MolecularDynamics #simulation #CompChem #MolBio #StructuralBiology #GPCR communities!
Feedback and ideas are always welcome.
#gpcr #StructuralBiology #molbio #compchem #simulation #moleculardynamics #receptor #opioid #signaling #forcefield #DNA #enzyme #opensource #preprint
Martin Vögele · @martinvoegele
184 followers · 24 posts · Server fediscience.orgAn overview paper on recent updates to GPCRdb:
https://doi.org/10.1093/nar/gkac1013
THebertMcGill · @THebert
16 followers · 160 posts · Server mas.to
RT @ArrestinBot
The association of ARRB1 polymorphisms with response to antidepressant treatment in depressed patients
#pharmacology #signaling #gpcr
Sébastien Fiorucci · @sebfiorucci
0 followers · 1 posts · Server mstdn.socialHello world,
I'm associate professor at Université Côte d'Azur located in Nice (France) and my research interests are #compchem #cheminformatics #AI #ML #GPCR #olfaction and #taste
#taste #olfaction #gpcr #ml #AI #Cheminformatics #compchem
THebertMcGill · @THebert
16 followers · 160 posts · Server mas.to
RT @ArrestinBot
Biased Activation Mechanism Induced by GPCR Heterodimerization: Observations from μOR/δOR Dimers
#pharmacology #signaling #gpcr
THebertMcGill · @THebert
16 followers · 160 posts · Server mas.to
RT @zenbrainest
This is a nice use of MD simulations for drug design at #gpcr https://twitter.com/Thue_Schwartz/status/1592025749841928192
THebertMcGill · @THebert
16 followers · 160 posts · Server mas.to
RT @ArrestinBot
Modulating the affinity and signaling bias of cannabinoid receptor 1 antagonists
#pharmacology #signaling #gpcr
Martin Vögele · @martinvoegele
172 followers · 27 posts · Server fediscience.orgGreat new paper about how #gpcr dimerization influences their signaling bias — from the labs of Michel Bouvier, Patrick Barth, Andy Chevigne, and Martine Smit:
https://www.nature.com/articles/s41467-022-34382-7