Referenced link: https://phys.org/news/2023-06-visualize-communication-protein-coupled-receptors-paving.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-06-visualize-communication-protein-coupled-receptors-paving.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1666167335520985088#m
Researchers visualize communication of #Gprotein-coupledreceptors, paving way for new #drugdiscovery @MolecularCell https://linkinghub.elsevier.com/retrieve/pii/S1097276523003209 https://phys.org/news/2023-06-visualize-communication-protein-coupled-receptors-paving.html
A major #hydrogenbond network within #Angiotensin II #receptor 1 determines signaling towards #Gq #Gprotein or beta-#arrestin in response to balanced or biased receptor agonists
#CryoEM structural and functional data by Haitao Zhang and coworkers with implications for #pharmacological targeting to control #bloodpressure and confer heart protection
https://www.embopress.org
/doi/10.15252/embj.2022112940
#hydrogenbond #angiotensin #receptor #gq #gprotein #arrestin #cryoem #pharmacological #BloodPressure
Development of #biosensor for real-time detection of the #Gprotein molecular switch.
https://phys.org/news/2023-03-biosensor-real-time-g-protein-molecular.html