Clear trends in hospital Group A strep admissions in UK. ⬇️ during and ⬆️ after #COVID19.

This is national Hospital Episode Statistics , which matches UKHSA data.

Next question: what exactly drove the recent rise?

Hospital admissions for group A streptococcal infections in England: current rates and historical perspective
#GAS #StrepA #GroupAstrep #bacteria #microbiology #IDMastodon #medicine #MedMastodon #infectiousdiseases
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00428-0/fulltext?dgcid=raven_jbs_aip_email

Infection with Streptococcus pyogenes after childbirth can have life threatening consequences. Here, Catton et al. show that the epidemiologically associated bacterial R28 protein targets the human CEACAM1 receptor to facilitate the pathogenesis of bacterial sepsis.
#GroupAstrep #StrepA #science #MedMastodon #IDMastodon #immunology #academicchatter

https://www.nature.com/articles/s41467-023-37732-1#Sec9

Interesting to see drop in big spike in invasive Group A strep notifications in England.

Big question is if there is going to be another peak now we enter the 'usual' season, or whether this was a solitary (big) early peak.

#IDMastodon #MedMastodon #GroupAstrep #GAS #iGAS #bacteria #microbiology
https://www.gov.uk/government/publications/group-a-streptococcal-infections-activity-during-the-2022-to-2023-season/group-a-streptococcal-infections-10th-update-on-seasonal-activity-in-england

CDC investigating possible increase in invasive #groupAstrep infections https://www.abcactionnews.com/news/national/cdc-investigating-possible-increase-in-invasive-group-a-strep-infection

CDC investigating possible increase in invasive #groupAstrep infections https://www.abcactionnews.com/news/national/cdc-investigating-possible-increase-in-invasive-group-a-strep-infection

👉 Group A streptococci are experts at avoiding and disarming human antibodies with no available vaccines or antibody treatments. This study presents a novel interaction mechanism between antibodies & antigens that can induce protective immune function against group A streptococci.

#StrepA #GroupAStrep #immunefunction

By W. Bahnan, P. Nordenfelt & colleagues @Lundsuni

Full #openaccess article: https://doi.org/10.15252/emmm.202216208

See also: bit.ly/3HpORVH

Scarlet fever is soaring in UK after pandemic lull; invasive infections kill 8 - Enlarge / A microscope image of Streptococcus pyogenes, a common type o... - https://arstechnica.com/?p=1902735 #invasivegroupastrep #groupastreptococci #respiratoryviruses #infectiousdisease #publichealth #scarletfever #antibiotics #groupastrep #strepthroat #children #science #viruses #strepa #cdc #nhs #uk

RT @UKHSA@twitter.com

Our latest blog explains what Group A Strep is and the infections it causes as well as how it is spread and what to look out for when your child is unwell. There is also info on Invasive Group A Strep (iGAS).

Read more ➡ https://ukhsa.blog.gov.uk/2022/12/05/group-a-strep-what-you-need-to-know/
#GroupAStrep #StrepA

🐦🔗: https://twitter.com/UKHSA/status/1599768294881316865

Despite platform issues, no reason to shun great content on #twitter

Excellent thread on what we know re #GroupAStrep so far and papers published on how challenging it is to stop transmission #IDMastadon #MedMastodon #microbiology

https://twitter.com/Grampospath/status/1599408274264449028?s=20&t=LrxmC4Y89XdllaCXm6K6Cg

#groupAstrep #鏈球菌 #kid #UK

英國已有4名孩童感染A型鏈球菌後身亡

A型鏈球菌感染後可能出現喉嚨痛、發燒、輕微皮膚感染等症狀，少數案例可能會演變為重症導致死亡

猩紅熱亦是由A型鏈球菌引起，初始症狀類似流感，之後起皮疹，舌頭呈現草莓舌態

🔗：https://www.theguardian.com/science/2022/dec/02/fourth-child-dies-in-uk-after-contracting-step-a-infection