New NIOO publication: Dynamic effects of #probiotic formula ecologic®825 on human small intestinal #ileostoma #microbiota: a network theory approach. #gutmicrobiota #metabolites #sequencing
https://doi.org/10.1080/19490976.2023.2232506

Referenced link: https://phys.org/news/2023-05-reveals-gut-microbiota-ferment-carbon.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-05-reveals-gut-microbiota-ferment-carbon.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1659558278685138948#m

Study reveals #gutmicrobiota can ferment carbon nanomaterials into organic metabolites @PNASNews @nature https://pnas.org/doi/10.1073/pnas.2218739120 https://phys.org/news/2023-05-reveals-gut-microbiota-ferment-carbon.html

Referenced link: https://phys.org/news/2023-04-chitin-consuming-insects-gut-microbiota.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-04-chitin-consuming-insects-gut-microbiota.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1649092753081466881#m

Chitin from consuming #insects can help both #gutmicrobiota and global health @ColoradoStateU @NatureFoodJnl https://phys.org/news/2023-04-chitin-consuming-insects-gut-microbiota.html

#Immunology #gutmicrobiota Help #TCells Heal Muscle @TheScientistLLC on work from @bolahanna, Mathis &co @harvardmed!
📌 https://www.the-scientist.com/news-opinion/gut-bacteria-help-t-cells-heal-muscle-study-71007#.ZBN9sXUX3jo.twitter
📌 https://www.hindawi.com/journals/mi/psi/
📌 https://www.hindawi.com/journals/mi/2019/1297675/

“New Research Links #IrritableBowelSyndrome to Reduced Bacterial Diversity

https://scitechdaily.com/new-research-links-irritable-bowel-syndrome-to-reduced-bacterial-diversity/

“The investigators combined their own dataset with 9 published, shared datasets, encompassing 576 IBS patients and 487 healthy controls”

#IrritableBowel #IBS @ibs #gutmicrobes #gutmicrobiome #gutmicrobiota

Our March issue is online!

This month’s cover highlights 2 articles on #GutMicrobiota dysfunctions in #myopathies.

Read also our review on peritoneal metastases & articles on a new PDX model for #melanoma, #AlcoholicLiverInjury, infancy-onset #diabetes, #MultipleSulfataseDeficiency, #Artemisinin in #BrainTumors & much more!

🗞️ Fully #openaccess: https://www.embopress.org/toc/17574684/2023/15/3

A. Jayaraman and S. Pettersson discuss the studies by Farini et al & Kalkan et al @EmboMolMed, that independently reported the potential role of the #GutMicrobiota in the pathogenesis of #DuchenneMuscularDystrophy.

N&V 🗞️: https://doi.org/10.15252/emmm.202217324

👉 Full articles #openaccess:
https://doi.org/10.15252/emmm.202216225
https://doi.org/10.15252/emmm.202216244

#GutMicrobiota are key to our overall health, yet advanced probiotic treatments are difficult to create.

The #EUfunded project, @NutraEurope, developed technologies that deliver ‘good bacteria’ into the gut more efficiently.

Read more: https://europa.eu/!GQn4hq

🐦🔗: https://n.respublicae.eu/CORDIS_EU/status/1613828653145591809

RT @ktguzz
"Biomarker-responsive engineered #probiotic diagnoses, records, and ameliorates inflammatory bowel disease in mice"

#ibs #gutmicrobiome #gutmicrobiota
https://www.sciencedirect.com/science/article/abs/pii/S1931312822005765

#oncologyresearch There is growing evidence that #gutmicrobiome also play an important role in tumorigenesis, progression, and immunotherapy of many neoplasms .particularly through interactions with the tumor microenvironment ,#Gutmicrobiota in multiple myeloma and possible mechanisms in MM development @FrontImmunol
https://www.frontiersin.org/articles/10.3389/fimmu.2022.1058272/full?utm_source=S-TWT&utm_medium=SNET&utm_campaign=ECO_FIMMU_XXXXXXXX_auto-dlvrit

#gutmicrobiota #gutmicrobiome #Clostridium #infection #fecaltransplant https://www.microbiota-site.com/news-on-microbiota/1161-fda-approves-first-fecal-microbiota-product.html

RT @helenebatina
3/3 [...] according to PCR analysis of #gutmicrobiota . The results demonstrate the relevance of #bacteriophages in the rehabilitation of the microbiota of patients who have undergone COVID-19 and received antibiotic treatment "

😍 Promising !!
#phages

@Jerome_Larche

An impressive panorama of Trimethylamine N-oxide/TMAO on👤aortic #EndothelialCell
⏫Traits of #TrainedImmunity/Inflammation
Metabolic reprogramming
Kinome & transcriptional network

Intriguing role of PERK & mitoROS

In addition to Liver, Aorta (#SmoothMuscleCell/#Pericyte/Fibroblast/Mɸ?) may🤔 also oxidize #GutMicrobiota-derived trimethylamine/TMA into Trimethylamine N-oxide/TMAO

What is the local/Aortic vs circulating TMAO level?🧐

Wait for🐭tissue-specific KO of FMO3 (Oxidizing TMA)😆

Dr. Xiaofeng Yang lab JCI insight 2022
https://insight.jci.org/articles/view/158183

Study: Eating foods with #antimicrobial compounds can help shape your #gutmicrobiota

https://food.news/2022-11-22-foods-antimicrobial-compounds-help-shape-gut-microbiota.html

#guthealth

Study: Eating foods with #antimicrobial compounds can help shape your #gutmicrobiota

https://food.news/2022-11-22-foods-antimicrobial-compounds-help-shape-gut-microbiota.html

#guthealth

Study: Eating foods with #antimicrobial compounds can help shape your #gutmicrobiota

https://www.naturalnews.com/2022-11-22-foods-antimicrobial-compounds-help-shape-gut-microbiota.html

#guthealth

Study: Eating foods with #antimicrobial compounds can help shape your #gutmicrobiota

https://www.naturalnews.com/2022-11-22-foods-antimicrobial-compounds-help-shape-gut-microbiota.html

#guthealth

#hostMicrobe #gutmicrobiota #gutmicrobiome #gutmicrobes #marine #freshwater #animal @MicrobioJC @biorxivpreprint #fish

Very pleased to present our latest work on the mechanisms of the gut-brain axis (https://doi.org/10.1101/2022.11.12.516113) and how the blood-brain barrier is affected in chronic kidney disease

Work was led by Sita Shah and co-authors Tobias Knausenberger, Emily Connell, Gwen Le Gall, Tom Hardy, David Randall, Kieran McCafferty, Magdi Yaqoob, Egle Solito, Michael Muller, Andrew Stachulski, Bobby Glen, David Vauzour and @BugsInYourGuts

People with CKD are at increased risk of stroke and brain blood vessel disease, but we don’t really know why. We looked at the role of the gut microbe-derived toxin p-cresol sulfate (pCS)

Using cell and mouse models we show that pCS activates the EGF receptor to cause metalloprotease release, damaging and weakening the blood-brain barrier

Importantly, we also showed that serum from patients undergoing haemodialysis for CKD damaged blood-brain barrier integrity in vitro, an effect we could block by treating with an EGF receptor inhibitor

We think this further highlights the importance of gut microbes in disease, and shows just how interlinked different organ systems are #gutkidneybrainaxis

And maybe EGF receptor inhibitors might be useful in modifying CKD stroke risk?

All of this was made possible by Alzheimer's Research UK awarding us a pilot project grant six years ago. Think we might have got a bit carried away with the amount of #gutbrainaxis work we did with it, but we are incredibly grateful!

#gutbrainaxis #BBB #CKD #cresolsulfate #kidney #gutmicrobiota #uraemia #Alzheimer'sResearchUK

Very pleased to present our latest work on the mechanisms of the gut-brain axis (https://doi.org/10.1101/2022.11.12.516113) and how the blood-brain barrier is affected in chronic kidney disease

Work was led by Sita Shah and co-authors Tobias Knausenberger, Emily Connell, Gwen Le Gall, Tom Hardy, David Randall, Kieran McCafferty, Magdi Yaqoob, Egle Solito, Michael Muller, Andrew Stachulski, Bobby Glen, David Vauzour and @BugsInYourGuts

People with CKD are at increased risk of stroke and brain blood vessel disease, but we don’t really know why. We looked at the role of the gut microbe-derived toxin p-cresol sulfate (pCS)

Using cell and mouse models we show that pCS activates the EGF receptor to cause metalloprotease release, damaging and weakening the blood-brain barrier

Importantly, we also showed that serum from patients undergoing haemodialysis for CKD damaged blood-brain barrier integrity in vitro, an effect we could block by treating with an EGF receptor inhibitor

We think this further highlights the importance of gut microbes in disease, and shows just how interlinked different organ systems are #gutkidneybrainaxis

And maybe EGF receptor inhibitors might be useful in modifying CKD stroke risk?

All of this was made possible by Alzheimer's Research UK awarding us a pilot project grant six years ago. Think we might have got a bit carried away with the amount of #gutbrainaxis work we did with it, but we are incredibly grateful!

#gutbrainaxis #BBB #CKD #cresolsulfate #kidney #gutmicrobiota #uraemia #Alzheimer'sResearchUK