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TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science
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RT @TumorBoardTues
4/#TumorBoardTuesday

⌚️Understanding timing of onset helps us better understand, differentiate, & manage TKI & ICI-related AEs 👇

#bonumce #OncTwitter #gyncsm #gynonc

Last updated 2 years ago
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TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science
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RT @TumorBoardTues
3/#TumorBoardTuesday

🟠Earn 🆓 🏆
🟠 ℹ️🔗bit.ly/3YRDkog

📸 Faculty disclosures & important CME info 👇

#bonumce #OncTwitter #gyncsm #gynonc #endometrialcancer #cme

Last updated 2 years ago
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TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science
Open media

RT @TumorBoardTues
4/#TumorBoardTuesday

⌚️Understanding timing of onset helps us better understand, differentiate, & manage TKI & ICI-related AEs 👇

#bonumce #OncTwitter #gyncsm #gynonc

Last updated 2 years ago
Original post

TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science

RT @TumorBoardTues
8/#TumorBoardTuesday

🔗bit.ly/3hYxu3R

🔴 Q4️⃣
During treatment w pembro + lenva, pt develops grade 3 HTN
🔴What is the most effective mgmt strategy for this patient? (CS = corticosteroid)

#bonumce #OncTwitter #gyncsm #gynonc #endometrialcancer #cme #posttest

Last updated 2 years ago
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TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science

RT @TumorBoardTues
2/#TumorBoardTuesday
🔗bit.ly/3YRDkog

🟢 Q 1️⃣
📊Diarrhea, nausea, & vomiting are common GI toxicities associated w pembro + lenvatinib combo therapy

🟢Which other tox may occur if these GI toxicities are not effectively managed?

#OncTwitter #gyncsm #gynonc #cme #PreTest

Last updated 2 years ago
Original post

TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science

RT @TumorBoardTues
5/#TumorBoardTuesday
🔗bit.ly/3YRDkog

🟢 Q 4️⃣
📊During treatment w pembro + lenva, pt develops grade 3 HTN
🟢What is the most effective mgmt strategy for this patient? (CS = corticosteroid)

#bonumce #OncTwitter #gyncsm #gynonc #endometrialcancer #cme #PreTest

Last updated 2 years ago
Original post

TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science

8/#TumorBoardTuesday

🔗bit.ly/3hYxu3R

🔴 Q4️⃣
During treatment w pembro + lenva, pt develops grade 3 HTN
🔴What is the most effective mgmt strategy for this patient? (CS = corticosteroid)

#bonumce #OncTwitter #gyncsm #gynonc #endometrialcancer #cme #posttest

Last updated 2 years ago
Original post

C. Harris Floudas · @chfloudas
70 followers · 378 posts · Server mstdn.social

Very nice RT @TumorBoardTuesday: 4/#TumorBoardTuesday

⌚️Understanding timing of onset helps us better understand, differentiate, & manage TKI & ICI-related AEs 👇

#gynonc #gyncsm #onctwitter #bonumce

Last updated 2 years ago
Original post

TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science
Open media

4/#TumorBoardTuesday

⌚️Understanding timing of onset helps us better understand, differentiate, & manage TKI & ICI-related AEs 👇

#bonumce #OncTwitter #gyncsm #gynonc

Last updated 2 years ago
Original post

TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science
Open media

3/#TumorBoardTuesday

🟠Earn 🆓 🏆
🟠 ℹ️🔗bit.ly/3YRDkog

📸 Faculty disclosures & important CME info 👇

#bonumce #OncTwitter #gyncsm #gynonc #endometrialcancer #cme

Last updated 2 years ago
Original post

TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science

5...4...3...2...1...it's the final countdown
⏰30m warning
🔥 w @DrMMurphy & @drteplinsky🔥

👩‍🏫B4 we begin...👩🏻‍🏫
✅Answer polls 👇
🔁Retweet & tag colleagues

---
RT @TumorBoardTues
2/#TumorBoardTuesday
🔗bit.ly/3YRDkog

🟢 Q 1️⃣
📊Diarrhea, nausea, & vomiting are common GI toxicities associated w…
twitter.com/TumorBoardTues/sta

#endometrialcancer #webinar #PreTest #TumorBoardTuesday #OncTwitter #medtwitter #gyncsm #gynonc #cme

Last updated 2 years ago
Original post

TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science

5/#TumorBoardTuesday
🔗bit.ly/3YRDkog

🟢 Q 4️⃣
📊During treatment w pembro + lenva, pt develops grade 3 HTN
🟢What is the most effective mgmt strategy for this patient? (CS = corticosteroid)

#bonumce #OncTwitter #gyncsm #gynonc #endometrialcancer #cme #PreTest

Last updated 2 years ago
Original post

TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science

2/#TumorBoardTuesday
🔗bit.ly/3YRDkog

🟢 Q 1️⃣
📊Diarrhea, nausea, & vomiting are common GI toxicities associated w pembro + lenvatinib combo therapy

🟢Which other tox may occur if these GI toxicities are not effectively managed?

#OncTwitter #gyncsm #gynonc #cme #PreTest

Last updated 2 years ago
Original post

TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science
Open media

RT @TumorBoardTues
2/#TumorBoardTuesday

🆓 CME > full info➕ref list🗒️& program archive
👉bit.ly/3VBGJEJ

🔑 info👇

#bonumce #OncTwitter #gyncsm #gynonc #endometrialcancer #medtweetorial #cme

Last updated 2 years ago
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TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science

RT @TumorBoardTues
3/#TumorBoardTuesday

🟢Which I/O +🎯tx combo is FDA approved for treatment of advanced or metastatic ?

nivo = nivolumab
dostarlimab = dostarlimab-gxly
pembro = pembrolizumab

#bonumce #OncTwitter #gynonc #gyncsm #endometrialcancer #endometrialcarcinoma

Last updated 2 years ago
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TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science

RT @TumorBoardTues
4/#TumorBoardTuesday

If you picked pembro + lenva…
You’re right🎉

Pembro (PD-1🎯mAb) + lenva (multi-🎯TKI)
➡️🏁accelerated approval adv EC in 2019

Ph3 confirmatory trial✅➡️-775
➡️full FDA approval 2021

#bonumce #OncTwitter #gyncsm #gynonc #endometrialcancer #keynote

Last updated 2 years ago
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TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science

RT @TumorBoardTues
5/#TumorBoardTuesday

most common gyn cancer in🇺🇸

Rates 📈
Est in 2022…
📊New cases: 69,950
📊Deaths: 12,550

Most pts dx early stage - gd prognosis✅

Approx 9% dx met disease➡️5y survival <20%➡️plat chemo SOC 1st line tx

#OncTwitter #gyncsm #gynonc #endometrialcancer

Last updated 2 years ago
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TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science

RT @TumorBoardTues
6/#TumorBoardTuesday

After progression on chemotx, tx for metastatic is influenced by tumor molecular subtype

🧬Cancer Genome Atlas ID’d 4️⃣ mol subclasses…
1️⃣POLE ultramutated
2️⃣dMMR/MSI-H
3️⃣Copy # low
4️⃣Copy # high

#bonumce #OncTwitter #gyncsm #gynonc #endometrialcancer

Last updated 2 years ago
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TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science
Open media

RT @TumorBoardTues
7/#TumorBoardTuesday

🧬Faulty DNA repair (dMMR/MSI-H)➡️high tumor mutation burden
➡️more tumor neoantigens
➡️sensitivity to ICI

💎Two FDA approved ICIs in dMMR/MSI-H :
🔹Pembro (PD-1 mAb)
🔹Dostarlimab (PD-1 mAb)

#bonumce #OncTwitter #gyncsm #gynonc #endometrialcancer

Last updated 2 years ago
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TumorBoardTuesday · @TumorBoardTuesday
114 followers · 2306 posts · Server mstdn.science
Open media

RT @TumorBoardTues
8/#TumorBoardTuesday

Pivotal trials leading to FDA approval in 2L met MSI-H/dMMR

🔸Pembro: (phase 2)
🔹Dostarlimab: (phase 1)

🔑Efficacy & safety data 📷👇

#bonumce #OncTwitter #gyncsm #gynonc #endometrialcancer #endometrialcarcinoma #keynote158 #garnet

Last updated 2 years ago
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