Giuseppe Michieli · @GMIK69
101 followers · 1931 posts · Server mstdn.scienceThe emergence of new #antigen #branches of #H9N2 avian #influenza virus in #China due to antigenic drift on #hemagglutinin through #antibody escape at immunodominant sites, Emerg Microbes Infect., https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2246582 #science #research #zoonoses #panzootic #epizootic #enzootic #pandemic
#antigen #branches #H9N2 #influenza #china #hemagglutinin #antibody #Science #research #Zoonoses #panzootic #epizootic #enzootic #pandemic
Giuseppe Michieli · @GMIK69
95 followers · 1861 posts · Server mstdn.scienceCharacterization of A/ #H7 #influenza virus global #antigenic diversity and key determinants in the #hemagglutinin globular head mediating A/ #H7N9 antigenic #evolution https://pubmed.ncbi.nlm.nih.gov/37565755/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1LGAx__djGAJ9poBzWGqPtjEbBDtz4ipSRRPUplmgHEyyF_Ihj&fc=None&ff=20230811141633&v=2.17.9.post6+86293ac #research #birdflu #pandemic #preparedness #vaccines
#h7 #influenza #antigenic #hemagglutinin #h7n9 #evolution #research #birdflu #pandemic #preparedness #vaccines
Giuseppe Michieli · @GMIK69
91 followers · 1799 posts · Server mstdn.scienceAn Advax-CpG55.2 adjuvanted recombinant #hemagglutinin #vaccine provides #immunity against #H7N9 #influenza in adult and neonatal mice, Vaccine: https://doi.org/10.1016/j.vaccine.2023.07.061 #research #immunology #birdflu #pandemic #preparedness
#hemagglutinin #vaccine #immunity #h7n9 #influenza #research #immunology #birdflu #pandemic #preparedness
Giuseppe Michieli · @GMIK69
54 followers · 968 posts · Server mstdn.science{Clade 2.3.2.1c #H5N1 viruses} ''Molecular analyses show that these viruses contained the #hemagglutinin (HA) gene #substitutions D94N, S133A, S155N, T156A, T188I and K189R known to increase binding to the human-type α2,6-linked sialic acid receptors'', Diversity of A(H5N1) clade 2.3.2.1c avian influenza viruses with evidence of reassortment in Cambodia, 2014-2016, https://doi.org/10.1371/journal.pone.0226108
#h5n1 #hemagglutinin #substitutions
aLFRe · @aLFRe
9 followers · 432 posts · Server mastodon.social
There are four types of viruses that cause the flu identified by a capital letter.
Wild aquatic birds are reservoirs for influenza A viruses.
that are identified by types of #hemagglutinin H and #neuraminidase N
two proteins of its capsid.
There have been two avian flu pandemics: #H5N1 in 2009 and #H7N9 in 2013. Tomorrow I'll tell you more
#hemagglutinin #neuraminidase #h5n1 #h7n9
beSpacific · @bespacific
34 followers · 93 posts · Server newsie.socialA #multivalent #nucleoside-#modified #mRNA #vaccine #against #all #known #influenza #virus #subtypes - Arevalo et al. #developed a nucleoside-modified messenger #RNA-#lipid #nanoparticle #vaccine #encoding #hemagglutinin #antigens from all 20 known #influenza A and B virus subtypes https://www.science.org/doi/10.1126/science.abm0271#.Y4DMJ5gdYY4.twitter
#multivalent #nucleoside #modified #mrna #vaccine #against #all #known #influenza #Virus #subtypes #developed #RNA #lipid #nanoparticle #encoding #hemagglutinin #antigens
Seth Thomas Scanlon · @ImmunoEditor
191 followers · 14 posts · Server mstdn.social
Today in #Science (@sciencemagazine), Claudia Arevalo, Scott Hensley, & al develop an #mRNA–#LipidNanoparticle #vaccine encoding #hemagglutinin antigens from all 20 known #influenza A & B virus subtypes/lineages! #Vaccination protected animals challenged w/ matched & mismatched viral strains!
In the same issue,
Alyson Kelvin & Darryl Falzarano write a wonderful Perspective on this important next step towards a #UniversalFluVaccine!
Article: bit.ly/Sci_abm0271
PS: bit.ly/Sci_adf0900
#IBV #IAV #universalfluvaccine #Vaccination #influenza #hemagglutinin #Vaccine #lipidnanoparticle #mrna #Science
Seth Thomas Scanlon · @ImmunoEditor
191 followers · 14 posts · Server mstdn.socialToday in @ScienceMagazine, Claudia Arevalo, Scott Hensley, & colleagues develop an #mRNA–#LipidNanoparticle #vaccine encoding #hemagglutinin antigens from all 20 known #influenza A & B virus subtypes/lineages! #Vaccination protected animals challenged w/ matched & mismatched viral strains!
In the same issue,
Alyson Kelvin & Darryl Falzarano write a wonderful Perspective on this important next step towards a #UniversalFluVaccine!
Article: bit.ly/Sci_abm0271
PS: bit.ly/Sci_adf0900
#IBV #IAV #universalfluvaccine #Vaccination #influenza #hemagglutinin #Vaccine #lipidnanoparticle #mrna