How do tumors promote #hematopoiesis outside the #BoneMarrow? @TheKingLab explores a new #PLOSBiology study of the mechanisms, which may hold the key to disrupting #immunosuppressive #tumor microenvironments. Primer: https://plos.io/3AYeiZY Paper: https://plos.io/41jMOJb
#tumor #immunosuppressive #plosbiology #bonemarrow #hematopoiesis
How do tumors promote #hematopoiesis outside the #BoneMarrow? @TheKingLab explores a new #PLOSBiology study of the mechanisms, which may hold the key to disrupting #immunosuppressive #tumor microenvironments. Primer: https://plos.io/3AYeiZY Paper: https://plos.io/41jMOJb
#tumor #immunosuppressive #plosbiology #bonemarrow #hematopoiesis
How do tumors promote #hematopoiesis outside the #BoneMarrow? @TheKingLab explores a new #PLOSBiology study of the mechanisms, which may hold the key to disrupting #immunosuppressive #tumor microenvironments. Primer: https://plos.io/3AYeiZY Paper: https://plos.io/41jMOJb
#tumor #immunosuppressive #plosbiology #bonemarrow #hematopoiesis
#Tumor-produced #interleukin-1α & LIF promote extramedullary #hematopoiesis. LIF directly expands #SplenicNicheCells while IL-1α induces TNFα production in hematopoietic stem & progenitor cells to activate splenic niche cells #PLOSBiology https://plos.io/41jMOJb
#plosbiology #splenicnichecells #hematopoiesis #interleukin #tumor
#Tumor-produced #interleukin-1α & LIF promote extramedullary #hematopoiesis. LIF directly expands #SplenicNicheCells while IL-1α induces TNFα production in hematopoietic stem & progenitor cells to activate splenic niche cells #PLOSBiology https://plos.io/41jMOJb
#plosbiology #splenicnichecells #hematopoiesis #interleukin #tumor
#Tumor-produced #interleukin-1α & LIF promote extramedullary #hematopoiesis. LIF directly expands #SplenicNicheCells while IL-1α induces TNFα production in hematopoietic stem & progenitor cells to activate splenic niche cells #PLOSBiology https://plos.io/41jMOJb
#plosbiology #splenicnichecells #hematopoiesis #interleukin #tumor
RT @dskrausemdphd@twitter.com
Do you want help planning your experiments related to #hematopoiesis? The CCEH consortium wants to help. You can find contact info here https://cceh.io/services or contact me directly for help w/ CFU, FACSorting, CD34 cells, mouse & xeno-transplant, etc. @NIDDKgov@twitter.com @YaleCCEH@twitter.com
🐦🔗: https://twitter.com/dskrausemdphd/status/1613173640752660482
#Epigenetic emergency switch improves defense against #infections.
https://medicalxpress.com/news/2022-12-epigenetic-emergency-defense-infections.html
#epigenetic #infections #hematopoiesis #h2bub1
If you have a spare moment in your day, please check out our November issue of Stem Cells. 😊 Also please submit your #stemcell manuscripts! 🙌🎉
#hematopoiesis #hematology #exosomes #gvhd #iPSCs #MSCs #cells #immunology #science
#stemcell #hematopoiesis #hematology #exosomes #gvhd #ipscs #mscs #cells #immunology #science
If you have a spare moment in your day, please check out our November issue of Stem Cells. 😊 Also please submit your #stemcell manuscripts! 🙌🎉
#hematopoiesis #hematology #exosomes #gvhd #iPSCs #MSCs #cells #immunology #science
#stemcell #hematopoiesis #hematology #exosomes #gvhd #ipscs #mscs #cells #immunology #science
What if we could recapitulate the complexity of human #bonemarrow in an #organoid model?
Enjoy this excellent research article by Abdullah Khan and colleagues at University of Birmingham and University of Oxford:
Human bone marrow organoids for #disease #modelling, discovery and validation of therapeutic #targets in hematological malignancies
Article in Cancer Discovery: https://aacrjournals.org/cancerdiscovery/article/doi/10.1158/2159-8290.CD-22-0199/710534/Human-bone-marrow-organoids-for-disease-modelling
#bonemarrow #organoid #disease #modelling #targets #hematopoiesis #myelofibrosis #leukemia
Migrated here from the @sciencemastodon server to join my fellow genomics peeps.
I am the Director of the Genomics Research Incubator (GRI) at Penn State. The GRI is a collaborative research lab that aims to enhance research and training providing expert advice, guidance, and direct access to #genomics and #epigenomics assays utilizing high throughput sequencing.
Personal research interests include mechanisms of gene regulation in #hematopoiesis. #chromatin
#introduction #genomics #Epigenomics #hematopoiesis #chromatin
The Blood Factory: New Research May Open the Door to Artificial Blood https://hackaday.com/2022/11/15/the-blood-factory-new-research-may-open-the-door-to-artificial-blood/ #artificialblood #CurrentEvents #hematopoiesis #erythrocytes #OriginalArt #transfusion #Featured #medicine #stemcell #Science #anemia #blood #News
#artificialblood #CurrentEvents #hematopoiesis #erythrocytes #OriginalArt #transfusion #Featured #medicine #stemcell #Science #anemia #blood #News
The Blood Factory: New Research May Open the Door to Artificial Blood - There were news stories afoot this week with somewhat breathless headlines that su... - https://hackaday.com/2022/11/15/the-blood-factory-new-research-may-open-the-door-to-artificial-blood/ #artificialblood #currentevents #hematopoiesis #erythrocytes #originalart #transfusion #featured #medicine #stemcell #science #anemia #blood #news
#news #blood #anemia #science #stemcell #medicine #featured #transfusion #originalart #erythrocytes #hematopoiesis #currentevents #artificialblood
The Blood Factory: New Research May Open the Door to Artificial Blood
https://hackaday.com/2022/11/15/the-blood-factory-new-research-may-open-the-door-to-artificial-blood/
#artificialblood #CurrentEvents #hematopoiesis #erythrocytes #OriginalArt #transfusion #Featured #medicine #stemcell #Science #anemia #blood #News
#artificialblood #CurrentEvents #hematopoiesis #erythrocytes #OriginalArt #transfusion #Featured #medicine #stemcell #science #anemia #blood #news
Hello science folks! #introduction
I am the Director of the Genomics Research Incubator (GRI), which is a collaborative research lab at Penn State (PSU) that serves to aid and enhance research by providing expert advice, guidance, technical training, and direct access to #genomics and epigenomics assays utilizing high throughput DNA #sequencing.
My personal research interests are focused on genomics and gene regulation in #hematopoiesis using mouse as a model system.
#introduction #genomics #sequencing #hematopoiesis
Arterial dictation of fetal #Hematopoiesis👹
Fetal bone marrow Bmx+ arterial #EndothelialCell (not Myh11+ mural cell) Wnt2->
⏫c-Kit+ HSPC β-catenin signals->
⏫colonization & transplant engraftment
Dr. Ralf Adams lab Nature Commmnications 2022
https://www.nature.com/articles/s41467-022-28775-x
#hematopoiesis #EndothelialCell