My Dresden colleagues have recently published a paper.
Carlotta Mayer (@c_ma_yer on the cross site) shows that #hepatocytes react to increased #bile #pressure by forming the #apical projections called bulkheads. This is also observed in #human #liver when bile pressure is increased to a pathological level. Upon further increase of bile pressure, bulkheads no longer hold the #canaliculi shape and form #rosettes.
#CellBiology #CellPolarity
https://doi.org/10.15252/embr.202357181
https://twitter.com/ZerialLab/status/1686028788658847744?s=20
#hepatocytes #bile #pressure #apical #human #liver #canaliculi #rosettes #cellbiology #cellpolarity
Referenced link: https://medicalxpress.com/news/2022-09-spike-sars-cov-metabolic-rewiring-hepatocytes.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2022-09-spike-sars-cov-metabolic-rewiring-hepatocytes.html
Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/medical_xpress/status/1572566359661314050#m
RT by @physorg_com: The spike of #SARS-CoV-2 promotes metabolic rewiring in #hepatocytes @CommsBio https://www.nature.com/articles/s42003-022-03789-9 https://medicalxpress.com/news/2022-09-spike-sars-cov-metabolic-rewiring-hepatocytes.html