Friday, we learned from Mikhail Kosiborod et al that #semaglutide helps patients with #HFpEF and #obesity. Today in Nature Medicine we learn why. It's all about providing real, effective obesity treatment.
https://conscienhealth.org/2023/08/hfpef-actually-treating-obesity-makes-the-difference/

“In patients with #HeartFailure with preserved ejection fraction #HFpEF and #obesity, treatment with #semaglutide (2.4 mg) led to larger reductions in symptoms and physical limitations, greater improvements in exercise function, and greater weight loss than placebo.”

https://www.nejm.org/doi/full/10.1056/NEJMoa2306963

RT @GiuseppeGalati_
👆👇 🔥 #HeartFailureAwarenessDays #HFAD 📣 D2
1day = 1theme
🧩 #HCM
🧩 #Amyloidosis
🧩 #StorageDiseases
are “Genetic causes of #HFpEF” not mimics
👉 Key is the Etiological Diagnosis
🍀 Position paper from #HFA @escardio & review
@mmamas1973 @dr_pavia

https://bit.ly/3p3eBjy

RT @GiuseppeGalati_
👆👇#SupervisedExercise in #HFpEF a statement from #AHA/#ACC
👉 Exercise beneficial in #HF across the full spectrum of #LVEF
@PierpaoloPel @DBelardoMD @pabeda1 @KardiologieHH @hvanspall @rahatheart1 @MiguelCamafort @VietHeartPA @gonzaeperez @MicheleSenni @DLBhattMD @KardiologieHH

RT @GiuseppeGalati_
#Top3 RCTs of #2022
🥇🏆#DELIVER : #SGLT2i Class I in #HFpEF & #HFmrEF (full spectrum of #LVEF)
🥈#STRONG_HF: High-Intensity (fast #GDMT start in #HFrEF better than step delayed approach)
🥉#REVIVED_PCI : Still too large use of #PCI in ischemic #HFrEF (need for more RCTs)
@gcfmd

RT @ACCinTouch
A 74 y/o 👴 w/ #HFpEF (EF 60%), #hypertension, & #CKD on hemodialysis presents for 🏥 follow-up. He was recently admitted for #heartfailure.

❓ Your patient should not be considered for a #SGLT2i at this time.
A. Fact
B. Fiction

Comment 👇 & learn more: https://bit.ly/3XGpynQ

RT @HanCardiomd
A RCT of Resistance Training Added to Caloric Restriction Plus #Aerobic Exercise Training in Obese #HFpEF

Adding resistance training to #diet and #exercise program may aid adults with #obesity, HFpEF

https://www.ahajournals.org/doi/10.1161/CIRCHEARTFAILURE.122.010161?cookieSet=1 @CircHF #HeartFailure @DrMarthaGulati @DBelardoMD