Use Organoid to study Plasticity & Organotypic traits of #EndothelialCell

3D Cardiac Microtissue
#hiPSC-cardiomyocyte, -Fibroblast, -EC

scRNAseq
hiPSC-cardiac mesoderm-EC vs
hiPSC-Paraxial mesoderm-EC
in🫀Organoid

Dr. Valeria Orlova lab bioRxiv 2022
https://www.biorxiv.org/content/10.1101/2022.11.22.517426v2.full

3D #Bioprinting of #OuterBloodRetinaBarrier #RetinalPigmentEpithelium + #Choriocapillaris

#hiPSC-RPE/EC/pericyte/fibroblast
PLGA nanoscaffold
Fibrin-gelatin

Modeling Dry & Wet #AMD🤠

RPE⏫Capillary Fenestration👈😎

Dr. Kapil Bharti lab Nature Methods 2022
https://www.nature.com/articles/s41592-022-01701-1

Vascularization improves function performance of #hiPSC-β Islet #Organoid 🤠

Ca2+ as a surrogate for insulin secretion to high throughput screening

A role of #Angiocrine #BMP4 signaling & #BasementMembrane

Dr. Maike Sander lab bioRxiv 2022
https://www.biorxiv.org/content/10.1101/2022.10.28.513298v1.full