Susanne Rafelski
is Deputy Director of Allen Institute for Cell Science
https://alleninstitute.org/person/susanne-rafelski/

"Integrated intracellular organization and its variations in human iPS cells"

How we can "know" a cell... observables:
molecular census (omics)
environment
organization
behavior

use #human #hiPSC as model

https://alleninstitute.org/news/the-interior-design-of-our-cells-2/

#SingleCell #imaging #CSSingleCells23 #OpenScience

RT @HaoYin20@twitter.com

PD-L1 KO
⏬#hiPSC-#YolkSacOrganoid differentiation into #Macrophage
⏬IFNGR1+IFNγ signals in hiPSC-Mφ
⏫Anti-Inflammatory signaling profile🤠
⏫TGFβ
⏬NOD/TNF/NFκB/IL17
Distinct from adult BM Mφ

@rio_sugimura@twitter.com lab bioRxiv 2022 @cao_handi@twitter.com @DavidXIANG2021@twitter.com
https://www.biorxiv.org/content/10.1101/2022.12.14.520176v1

🐦🔗: https://twitter.com/HaoYin20/status/1614237518819463169