The EMBO Journal · @embojournal
461 followers · 226 posts · Server sciencemastodon.com
Transcriptional and #chromatin profiling of human blood innate #lymphoid cell subsets sheds light on #HIV1 pathogenesis
Luban Lab and collaborators
https://www.embopress.org/doi/full/10.15252/embj.2023114153
kirt · @kirt
62 followers · 219 posts · Server zeroes.caHow long did it take us to discover that #HIV first infected humans half a century before western scientists noticed it?
As in the current dominant #HIV1 strain first went from chimps to humans in about the #1920s
There's been multiple #spillover events from multiple species, so this has probably been happening for 1000s of years? (but older #spillovers didn't get far because it's not very contagious)
tweeted https://twitter.com/evolving_string/status/1635681501965864960
#hiv #hiv1 #1920s #spillover #spillovers #1920shiv
Walter's News · @ThatsTheWayItIs
40 followers · 156 posts · Server mastodon.world
#FDA #approval of a new drug for treating #HIV1.
#Lenacapavir is the first of a new class of #Capsid_Inhibitor drugs
Capsid inhibitors block assembly of the HIV-1 virus' protein shell and interferes with two essential steps of the virus’ evolution.
Lenacapavir is estimated to cost $42,250 for the 1st yr. Subsequent years: $39,000 annually. Insurance coverage of capsid inhibitors is unknown.
"FDA Approves First-in-Class Drug for HIV"
Medscape
Lucy Hicks
20221222
https://bityl.co/GNSd
#fda #approval #hiv1 #lenacapavir #capsid_inhibitor
Eric's Risk Assessment · @EricCarroll
1336 followers · 1391 posts · Server zeroes.ca#SARSCoV2 and #HIV1 So Different yet so Alike. Immune Response at the Cellular and Molecular Level
"We considered features of the host immune response that are shared with HIV-1 and could account for the lymphopenia and other immune effects observed in #COVID19."
#sarscov2 #hiv1 #covid19 #SARS2 #immunology
gaby_wald · @gaby_wald
70 followers · 16249 posts · Server framapiaf.org#sciencedirect #review "HIV-1 and SARS-CoV-2: Patterns in the Evolution of Two Pandemic Pathogens" #HIV #HIV1 #SARSCoV2 #evolution #mutations #biology #virus #pathogens #patterns #variability #immuneescape ... https://www.sciencedirect.com/science/article/pii/S1931312821002407
#sciencedirect #review #hiv #hiv1 #SarsCoV2 #evolution #mutations #biology #virus #pathogens #patterns #variability #ImmuneEscape
gaby_wald · @gaby_wald
74 followers · 16277 posts · Server framapiaf.org#sciencedirect #review "HIV-1 and SARS-CoV-2: Patterns in the Evolution of Two Pandemic Pathogens" #HIV #HIV1 #SARSCoV2 #evolution #mutations #biology #virus #pathogens #patterns #variability #immuneescape ... https://www.sciencedirect.com/science/article/pii/S1931312821002407
#ImmuneEscape #variability #patterns #pathogens #virus #biology #mutations #evolution #SarsCoV2 #hiv1 #hiv #review #sciencedirect