Very happy to share our newly published #article "Sex differences in pituitary corticotroph excitability".

It is well known that sex differences exist in stress-related disorders, with women having twice the lifetime rate of depression compared to men and most anxiety disorders.

Corticotroph cells in the pituitary gland are a key player in the generation of hormonal stress responses. However, their contribution to sexually differential responses of the stress axis (which might underlie differences in stress-related disorders) is very poorly understood.

We found sex differences in the electrical activity of these cells, which could be related to differences in their gene expression pattern.

These findings shed light on the cellular mechanisms underlying sex differences in stress responses, contributing to a better understanding of stress-related disorders and potential avenues for diagnosis and treatment.

#stress #pituitary #research #electrophysiology #physiology #corticotrophs #hpa #anxiety

https://www.frontiersin.org/articles/10.3389/fphys.2023.1205162/full

Does anyone know how seabirds in Iceland are faring with Bird Flu? #HPA #Iceland @sjurdur

Aus leider aktuellem Anlass...

👉 Warum sollte man nicht in der #Elbe schwimmen?
👉 Was ist ein #Wasserrettungspunkt?
👉 Wie funktioniert die Rettung aus Lebensgefahr?

Wir erklären dies mit der
#DLRG und der #HPA
👇
https://m.youtube.com/watch?v=HQSr7geI5j8

Hamburg am #kleinerFreitag.
Der ⚓Hafenkapitän schaut nach dem Rechten. Oder sucht er die Hafenfähren? Man weiß es nicht. ;)

#patrouille #hpa #hafenamt

🍍 As we learn to use Mastodon, the use of hashtags is helpful, in order to search for content. Hashtags like #airsoft , #HPA, #speedsoft, #speedqb, you get the idea.

Hinzu kommt:
- Umschlag im Hafen wächst längst nicht so rasant wie angenommen
- Wirtschaftsbehörde und #HPA planen richtigerweise, mehr Güter per Bahn und Binnenschiff zu transportieren
- #Köhlbrandtunnel soll kommen und kostet Milliarden. Er leitet den Verkehr auf die nördliche Hafenroute.
#HafenHamburg

#Elbvertiefung gescheitert, Flussnatur kaputt, #Hafenkooperation in weiter Ferne und der #Schlick steht #HPA und #BWI bis zum Hals. Es ist zum In-die-Tischkante-beißen!

Warum muss der @Senat_Hamburg@twitter.com die Menschen so hinhalten? Wieso müssen sich die Politiker und ihre Kumpels von der #HPA unbedingt ein Hintertürchen für die Rodung offenhalten?
#VölliBleibt #RettetHamburgsNatur #JederBaumZählt

#kubernetes #hpa #custom "Building your own custom metrics API for Horizontal Pod Autoscaler" https://medium.com/swlh/building-your-own-custom-metrics-api-for-kubernetes-horizontal-pod-autoscaler-277473dea2c1

Stop asking me about scale to zero solutions for your Kubernetes cluster, just because you don't want to pay for your stateful (and therefore static) workloads.

Scale to zero is not designed to manage static workloads.
It is designed to run dynamic workloads at scale, by leveraging a serverless architecture to upscale or downscale your node pool when necessary.

Also, running a serverless solution means that you have to choose between costs and performance, so it is useful when you're running oneshot workloads, like batches.

It is not designed to run your WordPress website, despite you can even do that.
If you want to reduce costs for static workloads, then use the Horizontal Pod Autoscaler and let the cluster runs the bare minimum pod replicas to serve the requests the users are going to make.

#hpa #serverless #stateless #k8s

RT by https://nitter.snopyta.org/wohnraum_hh
Die Schildbürger bauen eine Brücke ...
https://www.ndr.de/nachrichten/hamburg/Eine-weitere-Panne-rund-um-die-Hamburger-Rethebruecke,rethebruecke142.html
#hpa #rethebrücke

#hpa #horizontal-pod-autoscaling #k8s #kubernetes party time horizontally scale all the pods 🎉